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Rudiger Kohling

Explore the profile of Rudiger Kohling including associated specialties, affiliations and a list of published articles. Areas
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Articles 134
Citations 1846
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Recent Articles
1.
Kolp H, Hackert J, Heerdegen M, Unger C, Sellmann T, Porath K, et al.
Epilepsy Res . 2025 Mar; 211:107535. PMID: 40023940
Objective: To study the effects of extracellular bromide in a novel immature rat pilocarpine model compared to the standard adolescent rat model. Methods: We employed an immature rat model of...
2.
Kragelund F, Spiliotis K, Heerdegen M, Sellmann T, Bathel H, Luttig A, et al.
Neurobiol Dis . 2024 Dec; 205():106779. PMID: 39725240
Background: Deep brain stimulation (DBS) targeting globus pallidus internus (GPi) is a recognised therapy for drug-refractory dystonia. However, the mechanisms underlying this effect are not fully understood. This study explores...
3.
Spiliotis K, Kohling R, Just W, Starke J
Front Netw Physiol . 2024 Aug; 4:1399347. PMID: 39171120
The striatum as part of the basal ganglia is central to both motor, and cognitive functions. Here, we propose a large-scale biophysical network for this part of the brain, using...
4.
Spiliotis K, Appali R, Fontes Gomes A, Payonk J, Adrian S, van Rienen U, et al.
Sci Rep . 2024 Aug; 14(1):18919. PMID: 39143173
A large-scale biophysical network model for the isolated striatal body is developed to optimise potential intrastriatal deep brain stimulation applied to, e.g. obsessive-compulsive disorder. The model is based on modified...
5.
Wormuth C, Papazoglou A, Henseler C, Ehninger D, Broich K, Haenisch B, et al.
Neural Plast . 2024 Aug; 2024:9946769. PMID: 39104708
Although several adult rat models of medial temporal lobe epilepsy (mTLE) have been described in detail, our knowledge of mTLE epileptogenesis in infant rats is limited. Here, we present a...
6.
Holl N, Heerdegen M, Zschorlich V, Kohling R, Kirschstein T
Brain Sci . 2024 Jun; 14(6). PMID: 38928603
High-frequency magnetic stimulation (HFMS) applied directly to the hippocampal slice preparation in vitro induces activity-dependent synaptic plasticity and metaplasticity. In addition, changes in synaptic transmission following HFMS involve the activation...
7.
Lange F, Gade R, Einsle A, Porath K, Reichart G, Maletzki C, et al.
Front Oncol . 2024 Jun; 14:1335401. PMID: 38835368
Background: The differentiation of high-grade glioma and brain tumors of an extracranial origin is eminent for the decision on subsequent treatment regimens. While in high-grade glioma, a surgical resection of...
8.
Muller S, Kartheus M, Hendinger E, Hubner D, Schnell E, Rackow S, et al.
Epilepsy Res . 2024 Jan; 200:107296. PMID: 38219422
Mutations within the Kv7.2 and Kv7.3 genes are well described causes for genetic childhood epilepsies. Knowledge on these channels in acquired focal epilepsy, especially in mesial temporal lobe epilepsy (mTLE),...
9.
Petereit C, Porath K, Rackow S, Kernig K, Hakenberg O, Kohling R, et al.
Pflugers Arch . 2023 Nov; 476(2):243-256. PMID: 37993748
Motility of detrusor smooth muscle includes adrenergic relaxation and cholinergic contraction. Since the latter may be deregulated in overactive bladder (OAB) pathophysiology, anticholinergics are the standard therapy but occasionally less...
10.
Spiliotis K, Butenko K, Starke J, van Rienen U, Kohling R
J Neural Eng . 2023 Nov; 20(6). PMID: 37988747
. Constructing a theoretical framework to improve deep brain stimulation (DBS) based on the neuronal spatiotemporal patterns of the stimulation-affected areas constitutes a primary target.. We develop a large-scale biophysical...