Rubin Dasgupta
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Explore the profile of Rubin Dasgupta including associated specialties, affiliations and a list of published articles.
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10
Citations
16
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Recent Articles
1.
Dasgupta R, Becker W, Petzold K
Nucleic Acids Res
. 2024 Sep;
52(19):11995-12004.
PMID: 39228364
Understanding mRNA regulation by microRNA (miR) relies on the structural understanding of the RNA-induced silencing complex (RISC). Here, we elucidate the structural organisation of miR-34a, which is de-regulated in various...
2.
Annecke H, Eidelpes R, Feyrer H, Ilgen J, Gurdap C, Dasgupta R, et al.
J Biomol NMR
. 2024 Aug;
78(4):249-264.
PMID: 39162911
Understanding the structure and function of nucleic acids in their native environment is crucial to structural biology and one focus of in-cell NMR spectroscopy. Many challenges hamper in-cell NMR in...
3.
Dasgupta R, Gupta K, de Groot H, Ubbink M
Magn Reson (Gott)
. 2023 Oct;
2(1):15-23.
PMID: 37904765
Laccases efficiently reduce dioxygen to water in an active site containing a tri-nuclear copper centre (TNC). The dynamics of the protein matrix is a determining factor in the efficiency in...
4.
Miao Q, Dekkers R, Gupta K, Overhand M, Dasgupta R, Ubbink M
Inorg Chem
. 2023 Feb;
62(9):3776-3787.
PMID: 36802549
Limiting the dynamics of paramagnetic tags is crucial for the accuracy of the structural information derived from paramagnetic nuclear magnetic resonance (NMR) experiments. A hydrophilic rigid 2,2',2″,2‴-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (DOTA)-like lanthanoid...
5.
Chatterjee S, Zhou J, Dasgupta R, Cramer-Blok A, Timmer M, van der Stelt M, et al.
Biochemistry
. 2021 Mar;
60(15):1178-1190.
PMID: 33749246
Phospholipase A/acyltransferase 3 (PLAAT3) and PLAAT4 are enzymes involved in the synthesis of bioactive lipids. Despite sequential and structural similarities, the two enzymes differ in activity and specificity. The relation...
6.
Dasgupta R, Gupta K, Elam D, Ubbink M, de Groot H
Solid State Nucl Magn Reson
. 2021 Mar;
113:101728.
PMID: 33744671
We demonstrate the efficacy of the REDOR-type sequences in determining dipolar coupling strength in a paramagnetic environment. Utilizing paramagnetic effects of enhanced relaxation rates and rapid electronic fluctuations in Cu(II)-(DL-Ala).HO,...
7.
Dasgupta R, Gupta K, de Groot H, Ubbink M
Chemphyschem
. 2021 Mar;
22(8):733-740.
PMID: 33682979
The enzyme laccase catalyzes the reduction of dioxygen to water at the trinuclear copper center (TNC). The TNC comprises a type-3 (T3) and a type-2 (T2) copper site. The paramagnetic...
8.
Dasgupta R, Gupta K, Nami F, de Groot H, Canters G, Groenen E, et al.
Biophys J
. 2020 Jun;
119(1):9-14.
PMID: 32531206
The trinuclear copper center (TNC) of laccase reduces oxygen to water with very little overpotential. The arrangement of the coppers and ligands in the TNC is known to be from...
9.
Bera S, Dhar J, Dasgupta R, Basu G, Chakraborti S, Chakrabarti P
Int J Biol Macromol
. 2018 Sep;
120(Pt B):2390-2398.
PMID: 30218729
Nanomaterials, such as graphene oxide (GO) are being studied to decipher their suitability in biomedical applications. This study investigate the effect on structure and function of hen egg white lysozyme...
10.
Dasgupta R, Ganguly H, Modugula E, Basu G
Biopolymers
. 2016 Jul;
108(1).
PMID: 27428516
Helix N-capping motifs often form hydrogen bonds with terminal amide groups which otherwise would be free. Also, without an amide hydrogen, proline (trans) is over-represented at helix N-termini (N1 position)...