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Ruben G Contreras

Explore the profile of Ruben G Contreras including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 450
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Recent Articles
1.
Contreras R, Torres-Carrillo A, Flores-Maldonado C, Shoshani L, Ponce A
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38892309
The sodium pump, or Na/K-ATPase (NKA), is an essential enzyme found in the plasma membrane of all animal cells. Its primary role is to transport sodium (Na) and potassium (K)...
2.
Campos-Blazquez J, Schuth N, Garay E, Clark A, Vogelsang U, Nachtegaal M, et al.
Metallomics . 2022 Sep; 14(10). PMID: 36151967
Contrasting reports exist in the literature regarding the effect of chloroquine treatment on cellular zinc uptake or secretion. Here, we tested the effect of chloroquine administration in the Drosophila model...
3.
Estrada N, Nunez-Vazquez E, Palacios A, Ascencio F, Guzman-Villanueva L, Contreras R
Front Immunol . 2021 Apr; 12:634497. PMID: 33868255
Programmed cell death (PCD) is an essential process for the immune system's development and homeostasis, enabling the remotion of infected or unnecessary cells. There are several PCD's types, depending on...
4.
Flores-Maldonado C, Albino-Sanchez M, Rodriguez-Callejas J, Estrada-Mondragon A, Leon-Galicia I, Maqueda-Alfaro R, et al.
Neuroscience . 2020 Jan; 439:275-286. PMID: 31954828
The use of antibodies to identify neuronal receptors, neurotransmitters, cytoskeletal elements or pathologic protein aggregates, ion channels, adhesion molecules or other cell-type specific markers, is common practice in neuroscience. Antibody...
5.
Castillo A, Ortuno-Pineda C, Flores-Maldonado C, Larre I, Martinez Rendon J, Hinojosa L, et al.
Cell Physiol Biochem . 2019 May; 52(6):1381-1397. PMID: 31075189
Background/aims: Ouabain, a well-known plant-derived toxin, is also a hormone found in mammals at nanomolar levels that binds to a site located in the a-subunit of Na⁺,K⁺-ATPase. Our main goal...
6.
Pereira D, Salgado M, Rocha S, Santos H, Villar J, Contreras R, et al.
J Cell Biochem . 2017 Nov; 119(4):3352-3362. PMID: 29130514
Cisplatin and other platinum-containing drugs have played a crucial role in anticancer treatments for over 30 years. However, treatment with cisplatin may cause serious side effects, such as myelosuppression, nausea,...
7.
Rocha S, Pessoa M, Neves L, Alves S, Silva L, Santos H, et al.
PLoS One . 2014 Oct; 9(10):e108776. PMID: 25290152
Cardiotonic steroids are used to treat heart failure and arrhythmia and have promising anticancer effects. The prototypic cardiotonic steroid ouabain may also be a hormone that modulates epithelial cell adhesion....
8.
Estrada N, Ascencio F, Shoshani L, Contreras R
Immunobiology . 2014 Aug; 219(12):964-74. PMID: 25097151
The toxic dinoflagellate Gymnodinium catenatum produces paralyzing shellfish poisons (PSPs) that are consumed and accumulated by bivalves. Previously, we recorded a decrease in hemocytes 24h after injection of PSPs (gonyautoxin...
9.
Garcia-Hernandez V, Flores-Maldonado C, Rincon-Heredia R, Verdejo-Torres O, Bonilla-Delgado J, Meneses-Morales I, et al.
J Cell Physiol . 2014 Jun; 230(1):105-15. PMID: 24909426
Epidermal Growth Factor (EGF) is a key regulator of epithelial paracellular permeability, a property that depends on tight junctions (TJ) and can be evaluated through the measurement of the transepithelial...
10.
Rincon-Heredia R, Flores-Benitez D, Flores-Maldonado C, Bonilla-Delgado J, Garcia-Hernandez V, Verdejo-Torres O, et al.
Exp Cell Res . 2013 Oct; 320(1):108-18. PMID: 24140471
In addition to being a very well-known ion pump, Na(+), K(+)-ATPase is a cell-cell adhesion molecule and the receptor of digitalis, which transduces regulatory signals for cell adhesion, growth, apoptosis,...