Ruben Aquino-Martinez
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Explore the profile of Ruben Aquino-Martinez including associated specialties, affiliations and a list of published articles.
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10
Citations
223
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Recent Articles
1.
Kasahara K, Kerby R, Aquino-Martinez R, Evered A, Cross T, Everhart J, et al.
NPJ Biofilms Microbiomes
. 2025 Jan;
11(1):12.
PMID: 39794320
Gut bacterial metabolism of dietary flavonoids results in the production of a variety of phenolic acids, whose contributions to health remain poorly understood. Here, we show that supplementation with the...
2.
Cao Y, Aquino-Martinez R, Hutchison E, Allayee H, Lusis A, Rey F
Mol Metab
. 2022 Jul;
64:101557.
PMID: 35870705
Background: The gut microbiome influences host physiology and cardiometabolic diseases by interacting directly with intestinal cells or by producing molecules that enter the host circulation. Given the large number of...
3.
Aquino-Martinez R, Hernandez-Vigueras S
J Clin Med
. 2021 Jan;
10(2).
PMID: 33466585
Periodontal bacteria dissemination into the lower respiratory tract may create favorable conditions for severe COVID-19 lung infection. Once lung tissues are colonized, cells that survive persistent bacterial infection can undergo...
4.
Aquino-Martinez R, Eckhardt B, Rowsey J, Fraser D, Khosla S, Farr J, et al.
J Periodontol
. 2020 Dec;
92(10):1483-1495.
PMID: 33341947
Background: Coinciding with other chronic comorbidities, the prevalence of periodontal disease increases with aging. Mounting evidence has established that senescent cells accumulate at sites of age-related pathologies, where they promote...
5.
Aquino-Martinez R, Khosla S, Farr J, Monroe D
Int J Mol Sci
. 2020 Oct;
21(20).
PMID: 33050175
The recent identification of senescent cells in periodontal tissues has the potential to provide new insights into the underlying mechanisms of periodontal disease etiology. DNA damage-driven senescence is perhaps one...
6.
Aquino-Martinez R, Rowsey J, Fraser D, Eckhardt B, Khosla S, Farr J, et al.
Bone
. 2020 Jan;
132:115220.
PMID: 31904537
Cellular senescence is associated with inflammation and extracellular matrix tissue remodeling through the secretion of proteins termed the senescence-associated secretory phenotype (SASP). Although osteocyte senescence in older individuals in the...
7.
Aquino-Martinez R, Monroe D, Ventura F
PLoS One
. 2019 Jan;
14(1):e0210301.
PMID: 30608979
Background: After bone resorption, ions and degraded organic components are co-released into the extracellular space. Ions and growth factors, although different in their biological nature, induce a common and coordinated...
8.
Aquino-Martinez R, Farr J, Weivoda M, Negley B, Onken J, Thicke B, et al.
J Bone Miner Res
. 2018 Oct;
34(1):135-144.
PMID: 30321475
Developing novel approaches to treat skeletal disorders requires an understanding of how critical molecular factors regulate osteoblast differentiation and bone remodeling. We have reported that (1) retinoic acid receptor-related orphan...
9.
Aquino-Martinez R, Angelo A, Pujol F
Stem Cell Res Ther
. 2017 Nov;
8(1):265.
PMID: 29145866
Background: Osteoinduction and subsequent bone formation rely on efficient mesenchymal stem cell (MSC) recruitment. It is also known that migration is induced by gradients of growth factors and cytokines. Degradation...
10.
Aquino-Martinez R, Artigas N, Gamez B, Rosa J, Ventura F
PLoS One
. 2017 May;
12(5):e0178158.
PMID: 28542453
Understanding the molecular events that regulate osteoblast differentiation is essential for the development of effective approaches to bone regeneration. In this study, we analysed the osteoinductive properties of extracellular calcium...