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Ruan Pimenta

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Articles 29
Citations 119
Followers 0
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Recent Articles
1.
Bellucci C, Hemerly T, Albuquerque L, Pimenta R, Schreiter V, Reis S, et al.
Int Neurourol J . 2024 Oct; 28(3):225-231. PMID: 39363413
Purpose: Recent research has highlighted the mechanotransducer PIEZO2 as a crucial factor in lower urinary tract function, demonstrating associations with bladder compliance (BC), bladder wall thickening, and elevated bladder pressure....
2.
Candido P, Pimenta R, Maluf F, Chiovatto C, Romao P, Baldavira C, et al.
Andrology . 2024 Jun; 13(2):396-406. PMID: 38925608
Background: Peyronie's disease is characterized by the formation of fibrotic plaques in the penile tunica albuginea. Effective treatments are limited, warranting the investigation of new promising therapies, such as the...
3.
Dos Santos P, da Silva Gomes P, Romao P, Maluf F, Guimaraes V, Candido P, et al.
Biochem Genet . 2024 Mar; 63(1):817-831. PMID: 38522065
Bladder carcinoma (BC) is the tenth most frequent malignancy worldwide, with high morbidity and mortality rates. Despite recent treatment advances, high-grade BC and muscle-invasive BC present with significant progression and...
4.
Dos Santos G, Viana N, Pimenta R, de Camargo J, Guimaraes V, Romao P, et al.
Cancer Genet . 2024 Mar; 284-285:20-29. PMID: 38503134
Introduction: Search for new clinical biomarkers targets in prostate cancer (PC) is urgent. Telomeres might be one of these targets. Telomeres are the extremities of linear chromosomes, essential for genome...
5.
Pimenta R, Malulf F, Romao P, Caetano G, da Silva K, Ghazarian V, et al.
J Cancer Res Clin Oncol . 2024 Feb; 150(2):70. PMID: 38305916
Purpose: To assess the role of the p160 family, AR, and AR-V7 in different initial presentations of prostate cancer and their association with clinical endpoints related to tumor progression. Methods:...
6.
Lopes-Goncalves G, Costa-Pessoa J, Pimenta R, Tostes A, Da Silva E, Ledesma F, et al.
Sci Rep . 2023 Dec; 13(1):22685. PMID: 38114708
Focal segmental glomerulosclerosis (FSGS) is the leading cause of nephrotic syndrome, which is characterized by podocyte injury. Given that the pathophysiology of nondiabetic glomerulosclerosis is poorly understood and targeted therapies...
7.
Camargo J, Viana N, Pimenta R, Guimaraes V, Santos G, Candido P, et al.
Int J Mol Sci . 2023 Oct; 24(19). PMID: 37834295
Prostate cancer (PCa) has a high prevalence and represents an important health problem, with an increased risk of metastasis. With the advance of CRISPR-Cas9 genome editing, new possibilities have been...
8.
Pimenta R, Camargo J, Goncalves G, Ghazarian V, Candido P, Guimaraes V, et al.
Mol Biol Rep . 2023 Jul; 50(9):7333-7345. PMID: 37439896
Background: Previously, we demonstrated that cholesterol triggers the increase in p300/CBP-associated factor (PCAF), targeted by miR-17-5p. The p300, IL-6, PCAF, and miR-17-5p genes have important and contradictory roles in inflammation...
9.
Pimenta R, Mioshi C, Goncalves G, Candido P, Camargo J, Guimaraes V, et al.
Int J Mol Sci . 2023 Jun; 24(11). PMID: 37298588
MicroRNAs (miRNAs) have gained a prominent role as biomarkers in prostate cancer (PCa). Our study aimed to evaluate the potential suppressive effect of miR-137 in a model of advanced PCa...
10.
Pimenta R, Camargo J, Candido P, Ghazarian V, Goncalves G, Guimaraes V, et al.
Cell Physiol Biochem . 2022 Dec; 56(S4):1-15. PMID: 36458578
Background/aims: Cholesterol modulates intratumoral androgenic signaling in prostate cancer; however, the molecular mechanisms underlying these changes in castration-resistant prostate cancer (CRPC) are not fully elucidated. Herein, we investigated the effect...