» Authors » Roxanne Lofredi

Roxanne Lofredi

Explore the profile of Roxanne Lofredi including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 25
Citations 354
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
11.
Lofredi R, Okudzhava L, Irmen F, Brucke C, Huebl J, Krauss J, et al.
NPJ Parkinsons Dis . 2023 Jan; 9(1):2. PMID: 36611027
Pathologically increased beta power has been described as a biomarker for Parkinson's disease (PD) and related to prolonged bursts of subthalamic beta synchronization. Here, we investigate the association between subthalamic...
12.
Lofredi R, Auernig C, Ewert S, Irmen F, Steiner L, Scheller U, et al.
Neuroimage . 2022 Aug; 262:119552. PMID: 35981644
Lead-DBS is an open-source, semi-automatized and widely applied software tool facilitating precise localization of deep brain stimulation electrodes both in native as well as in standardized stereotactic space. While automatized...
13.
Darcy N, Lofredi R, Al-Fatly B, Neumann W, Hubl J, Brucke C, et al.
Exp Neurol . 2022 Jun; 356:114150. PMID: 35732220
Current efforts to optimise subthalamic deep brain stimulation in Parkinson's disease patients aim to harness local oscillatory activity in the beta frequency range (13-35 Hz) as a feedback-signal for demand-based...
14.
Rauschenberger L, Guttler C, Volkmann J, Kuhn A, Ip C, Lofredi R
Exp Neurol . 2022 Jun; 355:114140. PMID: 35690132
Intracerebral recordings from movement disorders patients undergoing deep brain stimulation have allowed the identification of pathophysiological patterns in oscillatory activity that correlate with symptom severity. Changes in oscillatory synchrony occur...
15.
Feldmann L, Lofredi R, Neumann W, Al-Fatly B, Roediger J, Bahners B, et al.
NPJ Parkinsons Dis . 2022 Apr; 8(1):44. PMID: 35440571
Adaptive deep brain stimulation (aDBS) is a promising concept for feedback-based neurostimulation, with the potential of clinical implementation with the sensing-enabled Percept neurostimulator. We aim to characterize chronic electrophysiological activity...
16.
Lofredi R, Kuhn A
Handb Clin Neurol . 2022 Jan; 184:249-257. PMID: 35034739
Dystonia is a hyperkinetic movement disorder associated with loss of inhibition, abnormal plasticity, dysfunctional sensorimotor integration, and brain oscillatory dysfunctions at cortical and subcortical levels of the central nervous system....
17.
Feldmann L, Neumann W, Krause P, Lofredi R, Schneider G, Kuhn A
Eur J Neurol . 2021 Mar; 28(7):2372-2377. PMID: 33675144
Background And Purpose: Biomarkers for future adaptive deep brain stimulation still need evaluation in clinical routine. Here, we aimed to assess stimulation-induced modulation of beta-band activity and clinical symptoms in...
18.
Lofredi R, Auernig G, Irmen F, Nieweler J, Neumann W, Horn A, et al.
Brain . 2020 Nov; 144(1):44-52. PMID: 33253351
The subthalamic nucleus is part of a global stopping network that also includes the presupplementary motor area and inferior frontal gyrus of the right hemisphere. In Parkinson's disease, subthalamic deep...
19.
Scheller U, Lofredi R, van Wijk B, Saryyeva A, Krauss J, Schneider G, et al.
Mov Disord . 2019 Sep; 34(11):1734-1739. PMID: 31483903
Objective: This study investigates the association between pallidal low-frequency activity and motor sign severity in dystonia after chronic deep brain stimulation for several months. Methods: Local field potentials were recorded...
20.
Lofredi R, Tan H, Neumann W, Yeh C, Schneider G, Kuhn A, et al.
Neurobiol Dis . 2019 Mar; 127:462-471. PMID: 30898668
Bradykinesia is reported to correlate with subthalamic beta power (13-35 Hz) recorded at rest in Parkinson's disease (PD). Pilot studies suggest adaptive deep brain stimulation triggered by amplitude threshold crossings...