Roxanne Lofredi
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Explore the profile of Roxanne Lofredi including associated specialties, affiliations and a list of published articles.
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25
Citations
354
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Recent Articles
1.
Butenko K, Neudorfer C, Dembek T, Hollunder B, Meyer G, Li N, et al.
Proc Natl Acad Sci U S A
. 2025 Jan;
122(2):e2417617122.
PMID: 39773021
Deep brain stimulation is an efficacious treatment for dystonia. While the internal pallidum serves as the primary target, recently, stimulation of the subthalamic nucleus (STN) has been investigated. However, optimal...
2.
Lofredi R, Feldmann L, Krause P, Scheller U, Neumann W, Krauss J, et al.
Nat Commun
. 2024 Sep;
15(1):8475.
PMID: 39349466
Dystonia is a hyperkinetic movement disorder that has been associated with an imbalance towards the direct pathway between striatum and internal pallidum, but the neuronal underpinnings of this abnormal basal...
3.
Brickwedde M, Anders P, Kuhn A, Lofredi R, Holtkamp M, Kaindl A, et al.
Transl Psychiatry
. 2024 Aug;
14(1):341.
PMID: 39181883
Magnetoencephalography (MEG) allows the non-invasive measurement of brain activity at millisecond precision combined with localization of the underlying generators. So far, MEG-systems consisted of superconducting quantum interference devices (SQUIDS), which...
4.
Goede L, Oxenford S, Kroneberg D, Meyer G, Rajamani N, Neudorfer C, et al.
Mov Disord
. 2024 Jul;
39(11):1971-1981.
PMID: 39051611
Background: Recent imaging studies identified a brain network associated with clinical improvement following deep brain stimulation (DBS) in Parkinson's disease (PD), the PD response network. Objectives: This study aimed to...
5.
Butenko K, Neudorfer C, Dembek T, Hollunder B, Meyer G, Li N, et al.
medRxiv
. 2024 Jun;
PMID: 38903109
Deep brain stimulation is a viable and efficacious treatment option for dystonia. While the internal pallidum serves as the primary target, more recently, stimulation of the subthalamic nucleus (STN) has...
6.
Mathiopoulou V, Lofredi R, Feldmann L, Habets J, Darcy N, Neumann W, et al.
NPJ Parkinsons Dis
. 2024 Apr;
10(1):77.
PMID: 38580641
Subthalamic beta band activity (13-35 Hz) is known as a real-time correlate of motor symptom severity in Parkinson's disease (PD) and is currently explored as a feedback signal for closed-loop...
7.
Bahners B, Lofredi R, Sander T, Schnitzler A, Kuhn A, Florin E
Brain Stimul
. 2024 Jan;
17(1):109-111.
PMID: 38244771
No abstract available.
8.
Merk T, Kohler R, Peterson V, Lyra L, Vanhoecke J, Chikermane M, et al.
Res Sq
. 2023 Oct;
PMID: 37790428
Brain computer interfaces (BCI) provide unprecedented spatiotemporal precision that will enable significant expansion in how numerous brain disorders are treated. Decoding dynamic patient states from brain signals with machine learning...
9.
Lofredi R, Scheller U, Mindermann A, Feldmann L, Krauss J, Saryyeva A, et al.
Mov Disord
. 2023 Feb;
38(5):894-899.
PMID: 36807626
Background: Pallidal deep brain stimulation (DBS) effectively alleviates symptoms in dystonia patients, but may induce movement slowness as a side-effect. In Parkinson's disease, hypokinetic symptoms have been associated with increased...
10.
Feldmann L, Lofredi R, Al-Fatly B, Busch J, Mathiopoulou V, Roediger J, et al.
Mov Disord
. 2023 Jan;
38(4):692-697.
PMID: 36718788
Background: Subthalamic nucleus (STN) beta (13 - 35 Hz) activity is a biomarker reflecting motor state in Parkinson's disease (PD). Adaptive deep brain stimulation (DBS) aims to use beta activity...