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Rosemary S E Brown

Explore the profile of Rosemary S E Brown including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 268
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Recent Articles
1.
Pal T, McQuillan H, Wragg L, Brown R
Endocrinology . 2024 Nov; 166(1). PMID: 39497459
The importance of hormones in mediating a behavioral transition in mammals from a virgin or nonparenting state to parental state was established around 50 years ago. Extensive research has since...
2.
Menezes F, Wasinski F, de Souza G, Nunes A, Bernardes E, Dos Santos S, et al.
Endocrinology . 2024 May; 165(7). PMID: 38728240
GH acts in numerous organs expressing the GH receptor (GHR), including the brain. However, the mechanisms behind the brain's permeability to GH and how this hormone accesses different brain regions...
3.
Khant Aung Z, Ladyman S, Brown R
J Neuroendocrinol . 2024 Mar; 36(5):e13386. PMID: 38549242
Extensive research is undertaken in rodents to determine the mechanism underlying obesity-induced leptin resistance. While body weight is generally tightly controlled in these studies, the effect of age of experimental...
4.
Smiley K, Phillipps H, Fang C, Brown R, Grattan D
Front Behav Neurosci . 2023 Jul; 17:1227726. PMID: 37484521
Parenting involves major behavioral transitions that are supported by coordinated neuroendocrine and physiological changes to promote the onset of novel offspring-directed behaviors. In comparison to maternal care, however, the mechanisms...
5.
Hackwell E, Ladyman S, Brown R, Grattan D
Endocrinology . 2023 Mar; 164(5). PMID: 36960565
Lactation in mammals is associated with a period of infertility, which serves to direct maternal metabolic resources toward caring for the newborn offspring rather than supporting another pregnancy. This lactational...
6.
Swart J, Grattan D, Ladyman S, Brown R
J Neuroendocrinol . 2023 Jan; 35(7):e13232. PMID: 36691950
Maternal interactions with offspring are highly rewarding, which reinforces expression of essential caregiving behaviours that promote offspring survival. In rats, the rewarding effect of pups depends on reproductive state, with...
7.
Khant Aung Z, Masih R, Desroziers E, Campbell R, Brown R
J Neuroendocrinol . 2022 Nov; 34(12):e13206. PMID: 36416198
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy to affect women of reproductive-age world-wide. Hyperandrogenism is both a hallmark feature of PCOS, and is hypothesised to be an underlying...
8.
Smiley K, Brown R, Grattan D
J Neurosci . 2022 Sep; 42(44):8308-8327. PMID: 36163141
Parental care is critical for successful reproduction in mammals. Recent work has implicated the hormone prolactin in regulating male parental behavior, similar to its established role in females. Male laboratory...
9.
Georgescu T, Khant Aung Z, Grattan D, Brown R
Proc Natl Acad Sci U S A . 2022 Feb; 119(6). PMID: 35131854
Aggressive behavior is rarely observed in virgin female mice but is specifically triggered in lactation where it facilitates protection of offspring. Recent studies demonstrated that the hypothalamic ventromedial nucleus (VMN)...
10.
Georgescu T, Swart J, Grattan D, Brown R
Front Glob Womens Health . 2021 Dec; 2:767467. PMID: 34927138
Transition into motherhood involves profound physiological and behavioral adaptations that ensure the healthy development of offspring while maintaining maternal health. Dynamic fluctuations in key hormones during pregnancy and lactation induce...