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Rosellina M Mancina

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Articles 22
Citations 654
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Recent Articles
1.
Jamialahmadi O, De Vincentis A, Tavaglione F, Malvestiti F, Li-Gao R, Mancina R, et al.
Nat Med . 2025 Jan; 31(2):700. PMID: 39820106
No abstract available.
2.
Ciociola E, Dutta T, Sasidharan K, Kovooru L, Noto F, Pennisi G, et al.
Clin Mol Hepatol . 2024 Dec; PMID: 39716370
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global epidemic. MASLD has a strong genetic component, and a common missense variant (rs2642438) in the mitochondrial amidoxime-reducing component 1 (MARC1)...
3.
Jamialahmadi O, De Vincentis A, Tavaglione F, Malvestiti F, Li-Gao R, Mancina R, et al.
Nat Med . 2024 Dec; 30(12):3614-3623. PMID: 39653778
Metabolic dysfunction-associated steatotic liver disease (MASLD) is characterized by an excess of lipids, mainly triglycerides, in the liver and components of the metabolic syndrome, which can lead to cirrhosis and...
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Pennisi G, Maurotti S, Ciociola E, Jamialahmadi O, Bertolazzi G, Mirarchi A, et al.
Arterioscler Thromb Vasc Biol . 2024 Feb; 44(5):1086-1097. PMID: 38385290
Background: ANGPTL3 (angiopoietin-like protein 3) is a circulating protein with a key role in maintaining lipoprotein homeostasis. A monoclonal antibody against ANGPTL3 is an approved and well-tolerated treatment to reduce...
6.
Dutta T, Sasidharan K, Ciociola E, Pennisi G, Noto F, Kovooru L, et al.
Liver Int . 2024 Feb; 44(5):1219-1232. PMID: 38375985
Objective: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global health concern with no effective and specific drug treatment available. The rs2642438 minor allele in mitochondrial amidoxime-reducing component 1 (MARC1)...
7.
Sasidharan K, Caddeo A, Jamialahmadi O, Noto F, Tomasi M, Malvestiti F, et al.
Cell Rep Med . 2024 Jan; 5(1):101352. PMID: 38232700
Steatotic liver disease (SLD) prevails as the most common chronic liver disease yet lack approved treatments due to incomplete understanding of pathogenesis. Recently, elevated hepatic and circulating interleukin 32 (IL-32)...
8.
Albuquerque J, Medeiros A, Alves A, Jannes C, Mancina R, Pavanello C, et al.
Atherosclerosis . 2023 Oct; 383:117314. PMID: 37813054
Background And Aims: The early diagnosis of familial hypercholesterolaemia is associated with a significant reduction in cardiovascular disease (CVD) risk. While the recent use of statistical and machine learning algorithms...
9.
Baselli G, Jamialahmadi O, Pelusi S, Ciociola E, Malvestiti F, Saracino M, et al.
J Hepatol . 2022 Apr; 77(3):596-606. PMID: 35405176
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver disorders and has a strong heritable component. The aim of this study was to identify new...
10.
Mancina R, Sasidharan K, Lindblom A, Wei Y, Ciociola E, Jamialahmadi O, et al.
Nat Metab . 2022 Feb; 4(1):60-75. PMID: 35102341
Fatty liver disease (FLD) is a growing health issue with burdening unmet clinical needs. FLD has a genetic component but, despite the common variants already identified, there is still a...