Rory L Williams
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Explore the profile of Rory L Williams including associated specialties, affiliations and a list of published articles.
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12
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85
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Recent Articles
1.
Pisera A, Yu Y, Williams R, Liu C
bioRxiv
. 2024 Dec;
PMID: 39651169
Efficient methods for diversifying genes of interest (GOIs) are essential in protein engineering. For example, OrthoRep, a yeast-based orthogonal DNA replication system that achieves the rapid in vivo diversification of...
2.
Bhunia M, Stehn C, Jubenville T, Novacek E, Larsson A, Madala M, et al.
Neurooncol Adv
. 2024 Dec;
6(1):vdae188.
PMID: 39620202
Background: Malignant peripheral nerve sheath tumors (MPNSTs) can arise from atypical neurofibromas (ANF). Loss of the polycomb repressor complex 2 (PRC2) is a common event. Previous studies on PRC2-regulated genes...
3.
Rix G, Williams R, Hu V, Spinner A, Pisera A, Marks D, et al.
Science
. 2024 Nov;
386(6722):eadm9073.
PMID: 39509492
When nature evolves a gene over eons at scale, it produces a diversity of homologous sequences with patterns of conservation and change that contain rich structural, functional, and historical information...
4.
Paulk A, Williams R, Liu C
ACS Synth Biol
. 2024 Jul;
13(8):2629-2634.
PMID: 39052526
We recently developed "autonomous hypermutation yeast surface display" (AHEAD), a technology that enables the rapid generation of potent and specific antibodies in yeast. AHEAD pairs yeast surface display with an...
5.
Paulk A, Williams R, Liu C
bioRxiv
. 2024 Jun;
PMID: 38826191
We recently developed 'autonomous hypermutation yeast surface display' (AHEAD), a technology that enables the rapid generation of potent and specific antibodies in yeast. AHEAD pairs yeast surface display with an...
6.
Williams K, Larsson A, Keller B, Chaney K, Williams R, Bhunia M, et al.
bioRxiv
. 2024 Apr;
PMID: 38585724
Neurofibromatosis Type 1 (NF1) is a common cancer predisposition syndrome, caused by heterozygous loss of function mutations in the tumor suppressor gene . Individuals with NF1 develop benign tumors of...
7.
Williams R, Liu C
Science
. 2024 Jan;
383(6681):372-373.
PMID: 38271527
Orthogonal replication enables rapid continuous biomolecular evolution in .
8.
Rix G, Williams R, Spinner H, Hu V, Marks D, Liu C
bioRxiv
. 2023 Nov;
PMID: 38014077
When nature maintains or evolves a gene's function over millions of years at scale, it produces a diversity of homologous sequences whose patterns of conservation and change contain rich structural,...
9.
Williams R, Murray R
Nat Commun
. 2022 Nov;
13(1):6822.
PMID: 36357387
Advances in synthetic biology, bioengineering, and computation allow us to rapidly and reliably program cells with increasingly complex and useful functions. However, because the functions we engineer cells to perform...
10.
Khazaei T, Williams R, Bogatyrev S, Doyle J, Henry C, Ismagilov R
Sci Adv
. 2020 Aug;
6(33):eaba0353.
PMID: 32851161
Major changes in the microbiome are associated with health and disease. Some microbiome states persist despite seemingly unfavorable conditions, such as the proliferation of aerobe-anaerobe communities in oxygen-exposed environments in...