Roosheel S Patel
Overview
Explore the profile of Roosheel S Patel including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
900
Followers
0
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Recent Articles
1.
Akalu Y, Patel R, Taft J, Canas-Arranz R, Richardson A, Buta S, et al.
bioRxiv
. 2024 Jul;
PMID: 38979204
One-sentence Summary: Human inborn error of immunity-guided discovery and development of a broad-spectrum RNA antiviral therapy.
2.
Torre D, Fstkchyan Y, Ho J, Cheon Y, Patel R, DeGrace E, et al.
Mol Cell
. 2023 Nov;
83(23):4255-4271.e9.
PMID: 37995687
Endogenous retroviruses (ERVs) are remnants of ancient parasitic infections and comprise sizable portions of most genomes. Although epigenetic mechanisms silence most ERVs by generating a repressive environment that prevents their...
3.
Cohen P, DeGrace E, Danziger O, Patel R, Barrall E, Bobrowski T, et al.
Microbiol Spectr
. 2023 Sep;
:e0077623.
PMID: 37676044
Single-cell RNA sequencing (scRNA-Seq) studies have provided critical insight into the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). scRNA-Seq library...
4.
Prescott R, Pankow A, de Vries M, Crosse K, Patel R, Alu M, et al.
Respir Res
. 2023 Aug;
24(1):213.
PMID: 37635251
Background: The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect against respiratory pathogens. Human airway epithelial (HAE) cultures at air-liquid interface are...
5.
Gruber C, Patel R, Trachtman R, Lepow L, Amanat F, Krammer F, et al.
Cell
. 2023 Jul;
186(15):3325.
PMID: 37478820
No abstract available.
6.
Prescott R, Pankow A, de Vries M, Crosse K, Patel R, Alu M, et al.
bioRxiv
. 2023 Mar;
PMID: 36909601
The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect against respiratory pathogens. Human airway epithelial cultures at air-liquid interface (HAE) are a...
7.
Malle L, Patel R, Martin-Fernandez M, Stewart O, Philippot Q, Buta S, et al.
Nature
. 2023 Feb;
615(7951):305-314.
PMID: 36813963
Down's syndrome (DS) presents with a constellation of cardiac, neurocognitive and growth impairments. Individuals with DS are also prone to severe infections and autoimmunity including thyroiditis, type 1 diabetes, coeliac...
8.
Danziger O, Patel R, DeGrace E, Rosen M, Rosenberg B
PLoS Pathog
. 2022 Apr;
18(4):e1010464.
PMID: 35421191
Interferons establish an antiviral state through the induction of hundreds of interferon-stimulated genes (ISGs). The mechanisms and viral specificities for most ISGs remain incompletely understood. To enable high-throughput interrogation of...
9.
Jurczyszak D, Manganaro L, Buta S, Gruber C, Martin-Fernandez M, Taft J, et al.
PLoS Pathog
. 2022 Mar;
18(3):e1010405.
PMID: 35333911
Type I interferons (IFN-Is) are a group of potent inflammatory and antiviral cytokines. They induce IFN stimulated genes (ISGs), which act as proinflammatory mediators, antiviral effectors, and negative regulators of...
10.
Cohen P, DeGrace E, Danziger O, Patel R, Barrall E, Bobrowski T, et al.
bioRxiv
. 2021 Nov;
PMID: 34845443
Single cell RNA sequencing (scRNA-Seq) studies have provided critical insight into the pathogenesis of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2), the causative agent of COronaVIrus Disease 2019 (COVID-19). scRNA-Seq...