Rongjie Fu
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Explore the profile of Rongjie Fu including associated specialties, affiliations and a list of published articles.
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12
Citations
72
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Recent Articles
1.
Chen S, Hou J, Jaffery R, Guerrero A, Fu R, Shi L, et al.
J Immunother Cancer
. 2024 Sep;
12(9).
PMID: 39313308
Background: Hyperactivated protein arginine methyltransferases (PRMTs) are implicated in human cancers. Inhibiting tumor intrinsic PRMT5 was reported to potentiate antitumor immune responses, highlighting the possibility of combining PRMT5 inhibitors (PRMT5i)...
2.
Wang Y, Zhou J, He W, Fu R, Shi L, Dang N, et al.
Cell Rep
. 2024 Jul;
43(7):114459.
PMID: 38985674
Glycine- and arginine-rich (GAR) motifs, commonly found in RNA-binding and -processing proteins, can be symmetrically (SDMA) or asymmetrically (ADMA) dimethylated at the arginine residue by protein arginine methyltransferases. Arginine-methylated protein...
3.
Zhang L, He W, Fu R, Wang S, Chen Y, Xu H
Nucleic Acids Res
. 2023 Aug;
51(18):9880-9893.
PMID: 37615574
High-fidelity clustered regularly interspaced palindromic repeats (CRISPR)-associated protein 9 (Cas9) variants have been developed to reduce the off-target effects of CRISPR systems at a cost of efficiency loss. To systematically...
4.
Zhang L, He W, Fu R, Xu H
bioRxiv
. 2023 Mar;
PMID: 36993488
High-fidelity Cas9 variants have been developed to reduce the off-target effects of CRISPR systems at a cost of efficiency loss. To systematically evaluate the efficiency and off-target tolerance of Cas9...
5.
Wang Y, Xin C, Yu S, Xie Y, Zhang W, Fu R
Toxics
. 2022 Dec;
10(12).
PMID: 36548559
In this study, 24 surface water samples were collected from the main trunk/tributary of the Lijiang River during the wet season (April) and the dry season (December) in 2021. The...
6.
Yu S, Zhang W, Miao X, Wang Y, Fu R
Int J Environ Res Public Health
. 2022 Dec;
19(23).
PMID: 36497508
Three high-frequency sampling and monitoring experiments were performed at the Lutang and Luowei transects of the Liujiang River entrance and at the southeast exit of the Liuzhou during 2019 for...
7.
Fu R, He W, Dou J, Villarreal O, Bedford E, Wang H, et al.
Nat Commun
. 2022 Jan;
13(1):474.
PMID: 35078987
The specificity of CRISPR/Cas9 genome editing is largely determined by the sequences of guide RNA (gRNA) and the targeted DNA, yet the sequence-dependent rules underlying off-target effects are not fully...
8.
Wang Y, He K, Sheng B, Lei X, Tao W, Zhu X, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(4).
PMID: 33483420
RNA helicases play roles in various essential biological processes such as RNA splicing and editing. Recent in vitro studies show that RNA helicases are involved in immune responses toward viruses,...
9.
He W, Zhang L, Villarreal O, Fu R, Bedford E, Dou J, et al.
Nat Commun
. 2020 Feb;
11(1):1134.
PMID: 32098955
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
10.
He W, Zhang L, Villarreal O, Fu R, Bedford E, Dou J, et al.
Nat Commun
. 2019 Oct;
10(1):4541.
PMID: 31586052
High-throughput CRISPR-Cas9 knockout screens using a tiling-sgRNA design permit in situ evaluation of protein domain function. Here, to facilitate de novo identification of essential protein domains from such screens, we...