Ronald W Millard
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Explore the profile of Ronald W Millard including associated specialties, affiliations and a list of published articles.
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35
Citations
1387
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Recent Articles
1.
Huang W, Liang J, Feng Y, Jia Z, Jiang L, Cai W, et al.
Exp Cell Res
. 2018 May;
371(1):20-30.
PMID: 29842877
Although resident cardiac stem cells have been reported, regeneration of functional cardiomyocytes (CMs) remains a challenge. The present study identifies an alternative progenitor source for CM regeneration without the need...
2.
Gong M, Yu B, Wang J, Wang Y, Liu M, Paul C, et al.
Oncotarget
. 2017 Apr;
8(28):45200-45212.
PMID: 28423355
Mesenchymal stem cells (MSCs) have been found to benefit patients with a variety of ischemic diseases via promoting angiogenesis. It is also well established that exosomes secreted from MSCs deliver...
3.
Yu B, Yang Y, Liu H, Gong M, Millard R, Wang Y, et al.
PLoS One
. 2016 Mar;
11(3):e0151542.
PMID: 26962868
Background: Clusterin (Clu) is a stress-responding protein with multiple biological functions. Our preliminary microarray studies show that clusterin was prominently upregulated in mesenchymal stem cells (MSCs) overexpressing GATA-4 (MSCGATA-4). We...
4.
Kondo H, Kim H, Wang L, Okada M, Paul C, Millard R, et al.
Aging Cell
. 2015 Dec;
15(1):56-66.
PMID: 26637971
The low reprogramming efficiency in cells from elderly patients is a challenge that must be overcome. Recently, it has been reported that senescence-associated microRNA (miR)-195 targets Sirtuin 1 (SIRT1) to...
5.
Kang K, Ma R, Cai W, Huang W, Paul C, Liang J, et al.
Stem Cells Int
. 2015 Jun;
2015:659890.
PMID: 26074976
Background and Objective. Exosomes secreted from mesenchymal stem cells (MSC) have demonstrated cardioprotective effects. This study examined the role of exosomes derived from MSC overexpressing CXCR4 for recovery of cardiac...
6.
Cai W, Kang K, Huang W, Liang J, Feng Y, Liu G, et al.
J Cell Mol Med
. 2015 Apr;
19(8):1825-35.
PMID: 25824297
The chemokine (C-X-C motif) receptor 4 (CXCR4) is expressed on native cardiomyocytes and can modulate isolated cardiomyocyte contractility. This study examines the role of CXCR4 in cardiomyocyte response to ischaemia-reperfusion...
7.
Yu B, Kim H, Gong M, Wang J, Millard R, Wang Y, et al.
Int J Cardiol
. 2015 Jan;
182:349-60.
PMID: 25590961
Background: Exosomes play an important role in intercellular signaling and exert regulatory function by carrying bioactive molecules. This study investigated (1) the cardioprotective capabilities of exosomes derived from mesenchymal stem...
8.
Ribeiro M, Zhu H, Millard R, Fan G
Curr Angiogenes
. 2014 Nov;
2(1):54-59.
PMID: 25374792
Exosomes, a group of small vesicles (30-100 nm), originate when the inward budding of the endosomal membrane forms multivesicular bodies (MVBs). Exosomes are released into the extracellular space when the...
9.
Chang D, Wen Z, Wang Y, Cai W, Wani M, Paul C, et al.
PLoS One
. 2014 Oct;
9(10):e107296.
PMID: 25310410
Background And Objective: Implantation of cell-sheets into damaged regions of the heart after myocardial infarction (MI) has been shown to improve heart function. However, the tissue morphology following application of...
10.
Wen Z, Huang W, Feng Y, Cai W, Wang Y, Wang X, et al.
PLoS One
. 2014 Sep;
9(9):e104666.
PMID: 25251394
MicroRNAs have been appreciated in various cellular functions, including the regulation of angiogenesis. Mesenchymal-stem-cells (MSCs) transplanted to the MI heart improve cardiac function through paracrine-mediated angiogenesis. However, whether microRNAs regulate...