Ronald K Siu
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Explore the profile of Ronald K Siu including associated specialties, affiliations and a list of published articles.
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16
Citations
902
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Recent Articles
1.
Shen J, James A, Zhang X, Pang S, Zara J, Asatrian G, et al.
Am J Pathol
. 2016 Jan;
186(2):419-34.
PMID: 26772960
The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo...
2.
Yuan W, James A, Asatrian G, Shen J, Zara J, Tian H, et al.
J Orthop Sci
. 2013 May;
18(4):646-57.
PMID: 23686083
Background: Spinal fusion is among the most commonly performed orthopaedic procedures. Unfortunately, current treatments such as autologous bone grafting or recombinant proteins (BMP-2) have numerous clinical shortcomings. Here, we directly...
3.
Liu Y, Zheng Z, Zara J, Hsu C, Soofer D, Lee K, et al.
Biomaterials
. 2012 Sep;
33(34):8745-56.
PMID: 22959466
Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires multiple operations, device removal, long-term systemic antibiotics, and extended rehabilitation, and...
4.
James A, Zara J, Corselli M, Chiang M, Yuan W, Nguyen V, et al.
J Vis Exp
. 2012 Jun;
(63):e2952.
PMID: 22664543
Human perivascular stem cells (PSCs) can be isolated in sufficient numbers from multiple tissues for purposes of skeletal tissue engineering. PSCs are a FACS-sorted population of 'pericytes' (CD146+CD34-CD45-) and 'adventitial...
5.
Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, et al.
J Craniofac Surg
. 2012 Feb;
23(1):61-6.
PMID: 22337375
Nell-1, first identified by its overexpression in synostotic cranial sutures, is a novel osteoinductive growth and differentiation factor. To further define Nell-1's role in craniofacial patterning, we characterized defects of...
6.
Siu R, Zara J, Hou Y, James A, Kwak J, Zhang X, et al.
Tissue Eng Part A
. 2011 Sep;
18(3-4):252-61.
PMID: 21902605
Repair of cartilage due to joint trauma remains challenging due to the poor healing capacity of cartilage and adverse effects related to current growth factor-based strategies. NELL-1 (Nel-like molecule-1; Nel...
7.
Ten Berge D, Kurek D, Blauwkamp T, Koole W, Maas A, Eroglu E, et al.
Nat Cell Biol
. 2011 Aug;
13(9):1070-5.
PMID: 21841791
Pluripotent stem cells exist in naive and primed states, epitomized by mouse embryonic stem cells (ESCs) and the developmentally more advanced epiblast stem cells (EpiSCs; ref. 1). In the naive...
8.
Zhang X, Peault B, Chen W, Li W, Corselli M, James A, et al.
Tissue Eng Part A
. 2011 May;
17(19-20):2497-509.
PMID: 21615216
The search for novel sources of stem cells other than bone marrow mesenchymal stem cells (MSCs) for bone regeneration and repair has been a critical endeavor. We previously established an...
9.
Chen W, Zhang X, Siu R, Chen F, Shen J, Zara J, et al.
J Bone Miner Res
. 2011 May;
26(6):1230-41.
PMID: 21611965
Nell-1 is a growth factor required for normal skeletal development and expression of extracellular matrix proteins required for bone and cartilage cell differentiation. We identified the transcription factor nuclear factor...
10.
Li W, Zara J, Siu R, Lee M, Aghaloo T, Zhang X, et al.
Plast Reconstr Surg
. 2011 Feb;
127(2):580-587.
PMID: 21285762
Background: Effective regeneration of bone is critical for fracture repair and incorporation and healing of bone grafts used during orthopedic, dental, and craniofacial reconstructions. Nel-like molecule-1 (Nell-1) is a secreted...