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Roman Smidak

Explore the profile of Roman Smidak including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 99
Followers 0
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Recent Articles
1.
Holubowicz R, Du S, Felgner J, Smidak R, Choi E, Palczewska G, et al.
Nat Biomed Eng . 2024 Nov; 9(1):57-78. PMID: 39609561
Delivering ribonucleoproteins (RNPs) for in vivo genome editing is safer than using viruses encoding for Cas9 and its respective guide RNA. However, transient RNP activity does not typically lead to...
2.
Hong J, Salom D, Choi E, Du S, Tworak A, Smidak R, et al.
J Biol Chem . 2024 Jan; 300(3):105678. PMID: 38272218
Rhodopsin (Rho) and cone opsins are essential for detection of light. They respond via photoisomerization, converting their Schiff-base-adducted 11-cis-retinylidene chromophores to the all-trans configuration, eliciting conformational changes to activate opsin...
3.
Lewandowski D, Foik A, Smidak R, Choi E, Zhang J, Hoang T, et al.
JCI Insight . 2022 Jan; 7(4). PMID: 35015730
Adiponectin receptor 1 (ADIPOR1) is a lipid and glucose metabolism regulator that possesses intrinsic ceramidase activity. Mutations of the ADIPOR1 gene have been associated with nonsyndromic and syndromic retinitis pigmentosa....
4.
Korz V, Kremslehner C, Malikovic J, Hussein A, Feyissa D, Nagelreiter I, et al.
Front Aging Neurosci . 2021 Jan; 12:611572. PMID: 33488384
Cognitive processes require striatal activity. The underlying molecular mechanisms are widely unknown. For this reason the striatal transcriptome of young (YM), aged cognitively impaired (OMB), and unimpaired (OMG) male rats...
5.
Esteves F, Dos Santos-Pinto J, Ferro M, Sialana F, Smidak R, Rares L, et al.
J Proteome Res . 2020 Jun; 19(8):3044-3059. PMID: 32538095
Orb-weaving spiders use a highly strong, sticky and elastic web to catch their prey. These web properties alone would be enough for the entrapment of prey; however, these spiders may...
6.
Pretsch G, Sanadgol N, Smidak R, Lubec J, Korz V, Hoger H, et al.
Amino Acids . 2020 Apr; 52(4):543-553. PMID: 32236698
The aim of the current study was to investigate whether doublecortin (DCX), insulin-like growth factor receptor 1 (IGF-1R) and metabotropic glutamate receptor 5 (mGluR5) levels are indeed modified in the...
7.
Lubec J, Smidak R, Malikovic J, Feyissa D, Korz V, Hoger H, et al.
Front Aging Neurosci . 2019 Aug; 11:198. PMID: 31417400
Similar to humans, the normal aged rat population is not homogeneous in terms of cognitive function. Two distinct subpopulations of aged Sprague-Dawley rats can be identified on the basis of...
8.
Dos Santos-Pinto J, Esteves F, Sialana F, Ferro M, Smidak R, Rares L, et al.
Mol Omics . 2019 Jul; 15(4):256-270. PMID: 31268449
Orb-weaving spiders can produce different silk fibers, which constitute outstanding materials characterized by their high strength and elasticity. Researchers have tried to reproduce the fibers of these proteins synthetically and/or...
9.
Sialana F, Ribeiroda Silva Menegasso A, Smidak R, Hussein A, Zavadil M, Rattei T, et al.
Proteomics . 2019 May; 19(13):e1900094. PMID: 31115157
The olfactory conditioning of the bee proboscis extension reflex (PER) is extensively used as a paradigm in associative learning of invertebrates but with limited molecular investigations. To investigate which protein...
10.
Malikovic J, Vuyyuru H, Koefeler H, Smidak R, Hoger H, Kalaba P, et al.
Neurochem Int . 2019 May; 128:215-221. PMID: 31051212
There is growing evidence that lipids play a fundamental role in neuronal plasticity and learning and memory. Effects of nutrition on brain lipid composition and neuronal functioning are known, but...