Roman Halter
Overview
Explore the profile of Roman Halter including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
120
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Recent Articles
1.
Rodt T, Luepke M, Boehm C, Hueper K, Halter R, Glage S, et al.
PLoS One
. 2012 Oct;
7(9):e44427.
PMID: 23028537
Introduction: SPC-raf and SPC-myc transgenic mice develop disseminated and circumscribed lung adenocarcinoma respectively, allowing for assessment of carcinogenesis and treatment strategies. The purpose of this study was to investigate the...
2.
Rodt T, von Falck C, Dettmer S, Hueper K, Halter R, Hoy L, et al.
J Exp Clin Cancer Res
. 2012 Feb;
31:15.
PMID: 22348342
Background: SPC-c-Raf-1-BxB transgenic mice develop genetically induced disseminated lung adenocarcinoma allowing examination of carcinogenesis and evaluation of novel treatment strategies. We report on assessment of lung tumour growth kinetics using...
3.
Hueper K, Elalfy M, Laenger F, Halter R, Rodt T, Galanski M, et al.
PLoS One
. 2012 Feb;
7(2):e30432.
PMID: 22319569
Background: More than 100,000 chemicals are in use but have not been tested for their safety. To overcome limitations in the cancer bioassay several alternative testing strategies are explored. The...
4.
Rodt T, von Falck C, Dettmer S, Halter R, Maus R, Ask K, et al.
Respir Res
. 2010 Dec;
11:181.
PMID: 21176193
Background: Micro-computed tomography (micro-CT) is a novel tool for monitoring acute and chronic disease states in small laboratory animals. Its value for assessing progressive lung fibrosis in mice has not...
5.
Garaguso I, Halter R, Krzeminski J, Amin S, Borlak J
Anal Chem
. 2010 Sep;
82(20):8573-82.
PMID: 20866025
Metabolic activation of polycyclic aromatic hydrocarbons (PAH) may cause DNA adduct formation. While these are commonly detected by the ³²P-postlabeling assay, this method is not informative on the chemical nature...
6.
Fritzinger D, Dean R, Meschter C, Wong K, Halter R, Borlak J, et al.
Adv Exp Med Biol
. 2010 Aug;
703:151-62.
PMID: 20711713
The effect of complement depletion with humanized cobra venom factor (CVF) on retinal lesion development/neovascularization was determined in a mouse model of wet age-related macular degeneration (AMD). Mice were treated...
7.
von Falck C, Rodt T, Halter R, Spanel R, Galanski M, Borlak J
Front Biosci (Landmark Ed)
. 2009 Mar;
14(6):2193-202.
PMID: 19273193
The EGF-transgenic mouse is a genetic model of hepatocellular carcinoma that allows for a comprehensive study of signal pathways, molecular interactions and the evaluation of novel therapeutic concepts. In this...
8.
Rodt T, von Falck C, Halter R, Ringe K, Shin H, Galanski M, et al.
Front Biosci (Landmark Ed)
. 2009 Mar;
14(5):1939-44.
PMID: 19273175
Lung cancer is the most common cancer worldwide. Early detection might reduce morbidity. In this study we evaluate a microCT imaging algorithm to assess in-vivo tumour load and quantification of...
9.
Rutters H, Zurbig P, Halter R, Borlak J
Proteomics
. 2006 May;
6(10):3127-37.
PMID: 16688788
We report mapping of proteins of adenocarcinomas of the lung as a result of overexpression of the oncogenically activated N-terminal deletion mutant c-raf-1 BxB through usage of the human SP-C...
10.
Borlak J, Meier T, Halter R, Spanel R, Spanel-Borowski K
Oncogene
. 2005 Jan;
24(11):1809-19.
PMID: 15674348
Epidermal growth factor is an important mitogen for hepatocytes. Its overexpression promotes hepatocellular carcinogenesis. To identify the network of genes regulated through EGF, we investigated the liver transcriptome during various...