Roman Gardlik
Overview
Explore the profile of Roman Gardlik including associated specialties, affiliations and a list of published articles.
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46
Citations
577
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Recent Articles
1.
Belvoncikova P, Fejes A, Gromova B, Janovicova L, Farkasova A, Babal P, et al.
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076519
Alcohol-related liver disease (ALD) is a leading cause of chronic liver conditions globally. Chronic alcohol consumption induces liver damage through various mechanisms, including neutrophil extracellular trap (NET) formation. Extracellular DNA...
2.
Jasenovec T, Vazan R, Radosinska D, Gardlik R, Radosinska J
Molecules
. 2025 Feb;
30(3).
PMID: 39942762
Research on the effects of melatonin on erythrocyte deformability has yielded mixed results. While some studies reported improvements, others found no effect, and a few even noted a deterioration in...
3.
Radosinska D, Gaal Kovalcikova A, Gardlik R, Chomova M, Snurikova D, Radosinska J, et al.
Biology (Basel)
. 2024 Oct;
13(10).
PMID: 39452068
Type 2 diabetes mellitus has been referred to as being closely related to oxidative stress, which may affect brain functions and brain glucose metabolism due to its high metabolic activity...
4.
Fejes A, Belvoncikova P, Porcel Sanchis D, Borbelyova V, Celec P, Dzunkova M, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203771
Increasing evidence of sexual dimorphism in the pathophysiology of metabolic complications caused by sex steroids is under investigation. The gut microbiota represents a complex microbial ecosystem involved in energy metabolism,...
5.
Janovicova L, Kmetova K, Pribulova N, Janko J, Gromova B, Gardlik R, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36769306
Deoxyribonucleases (DNases) cleave extracellular DNA (ecDNA) and are under intense research as interventions for diseases associated with high ecDNA, such as acute live injury. DNase I treatment decreases morbidity and...
6.
Belvoncikova P, Splichalova P, Videnska P, Gardlik R
J Fungi (Basel)
. 2022 Oct;
8(10).
PMID: 36294611
The mycobiome is the fungal component of the human microbial ecosystem that represents only a small part of this environment but plays an essential role in maintaining homeostasis. Colonization by...
7.
Belvoncikova P, Maronek M, Gardlik R
Int J Mol Sci
. 2022 Sep;
23(18).
PMID: 36142642
Gut microbiota dysbiosis has recently been reported in a number of clinical states, including neurological, psychiatric, cardiovascular, metabolic and autoimmune disorders. Yet, it is not completely understood how colonizing microorganisms...
8.
Maronek M, Gardlik R
J Innate Immun
. 2022 Mar;
14(5):393-417.
PMID: 35263752
Citrullination of proteins is crucial for the formation of neutrophil extracellular traps (NETs) - strands of nuclear DNA expulsed in the extracellular environment along with antimicrobial proteins in order to...
9.
Liptak R, Gromova B, Gardlik R
Front Med (Lausanne)
. 2021 Sep;
8:665520.
PMID: 34557498
Fecal microbiota transplantation has been primarily investigated as a therapeutic tool for a number of gut disorders. Optimistic results from clinical studies on Clostridium difficile infection, inflammatory bowel disease and...
10.
Celec P, Janovicova L, Gurecka R, Koborova I, Gardlik R, Sebekova K
Physiol Genomics
. 2021 Jun;
53(7):309-318.
PMID: 34097532
Obesity is associated with chronic low-grade inflammation that eventually leads to metabolic complications. Extracellular DNA (ecDNA) is a damage-associated molecular pattern. Extracellular mitochondrial DNA can activate innate immunity. We hypothesized...