Romain Pauwels
Overview
Explore the profile of Romain Pauwels including associated specialties, affiliations and a list of published articles.
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15
Citations
769
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Recent Articles
1.
Schelfhout V, Van De Velde V, Maggi C, Pauwels R, Joos G
Ther Adv Respir Dis
. 2009 Nov;
3(5):219-26.
PMID: 19880429
Objective: We previously reported that the nonpeptide tachykinin NK(2) receptor antagonist SR48968 (saredutant) significantly inhibits neurokinin A-induced bronchoconstriction in patients with asthma. MEN11420 (nepadutant) is a bicyclic peptide tachykinin NK(2)...
2.
Pauwels R, Joos G, Fogarty C, Faiferman I, Hirschberg S, Vessey R, et al.
Pulm Pharmacol Ther
. 2007 Nov;
21(2):385-92.
PMID: 18023600
The objectives of this study were to determine the effect of single and repeat dosing with oral ondansetron, a 5-HT3-specific receptor blocker, on the degree and duration of bronchodilation induced...
3.
Derom E, Strandgarden K, Schelfhout V, Borgstrom L, Pauwels R
Respir Med
. 2007 Jun;
101(9):1931-41.
PMID: 17544264
Background: Little is known about the impact of COPD on lung deposition of inhaled drugs and the relationship between lung-dose and response of pulmonary function measurements. Methods: Nineteen patients with...
4.
Derom E, Van De Velde V, Marissens S, Engelstatter R, Vincken W, Pauwels R
Pulm Pharmacol Ther
. 2005 Jun;
18(5):328-36.
PMID: 15939311
The efficacy and systemic effects of ciclesonide, a novel glucocorticosteroid, inhaled via pressurized metered-dose inhaler (pMDI) were compared with fluticasone propionate pMDI in 26 patients with asthma, using a randomized,...
5.
Vermaelen K, Pauwels R
Am J Respir Crit Care Med
. 2005 May;
172(5):530-51.
PMID: 15879415
Dendritic cells (DCs) are leukocytes that are emerging as chief orchestrators of immune responses. The crucial task of DCs is the continuous surveillance of antigen-exposed sites throughout the body, and...
6.
Vestbo J, Soriano J, Anderson J, Calverley P, Pauwels R, Jones P
Respir Med
. 2004 Nov;
98(11):1045-50.
PMID: 15526804
The prevalence of chronic obstructive pulmonary disease (COPD) in women is increasing worldwide. Women may have greater susceptibility to COPD progression than men, and differences in efficacy and safety of...
7.
Vermaelen K, Pauwels R
Cytometry A
. 2004 Sep;
61(2):170-77.
PMID: 15382026
Background: The need to accurately discriminate dendritic cells (DCs) and macrophages (Mphs) in mouse lungs is critical given important biological differences. However, a validated flow cytometry-based method is still lacking,...
8.
Sehra S, Pynaert G, Tournoy K, Haegeman A, Matthys P, Tagawa Y, et al.
J Immunol
. 2003 Aug;
171(4):2080-9.
PMID: 12902514
Besides IgE, the Ab isotype that gives rise to sensitization and allergic asthma, the immune response to common inhalant allergens also includes IgG. Increased serum titers of allergen-specific IgG, induced...
9.
Vermaelen K, Cataldo D, Tournoy K, Maes T, Dhulst A, Louis R, et al.
J Immunol
. 2003 Jul;
171(2):1016-22.
PMID: 12847275
Dendritic cells (DCs) appear to be strategically implicated in allergic diseases, including asthma. Matrix metalloproteinase (MMP)-9 mediates transmigration of inflammatory leukocytes across basement membranes. This study investigated the role of...
10.
Vermaelen K, Pauwels R
Am J Respir Cell Mol Biol
. 2003 Apr;
29(3 Pt 1):405-9.
PMID: 12702544
Pulmonary dendritic cells (DC) can induce both tolerogenic as well as inflammatory immune responses in the lung. Conversely, little is known about the impact of ongoing airway inflammation on pulmonary...