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Rolf-Edgar Silber

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Articles 84
Citations 1554
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Recent Articles
1.
Hofmann B, Rae E, Puvogel U, Spatarelu M, Mohamed S, Bungaran A, et al.
J Clin Med . 2023 Dec; 12(24). PMID: 38137666
In view of the increasing age of cardiac surgery patients, questions arise about the expected postoperative quality of life and the hoped-for prolonged life expectancy. Little is known so far...
2.
Hofmann B, Gerull K, Bloch K, Riemer M, Erbs C, Frohlich A, et al.
PLoS One . 2020 Jun; 15(6):e0234847. PMID: 32598375
Background: The optimum risk score determining perioperative mortality and morbidity in cardiac surgery remains debated. Advanced glycation end products (AGEs) derived from glycaemic and oxidative stress accumulate to a comparable...
3.
Gergs U, Mangold W, Langguth F, Hatzfeld M, Hauptmann S, Bushnaq H, et al.
Sci Rep . 2019 Apr; 9(1):5610. PMID: 30948763
The mature mammalian myocardium contains composite junctions (areae compositae) that comprise proteins of adherens junctions as well as desmosomes. Mutations or deficiency of many of these proteins are linked to...
4.
Gergs U, Trapp T, Bushnaq H, Simm A, Silber R, Neumann J
Adv Med . 2019 Feb; 2019:2675972. PMID: 30719459
Heart failure and aging of the heart show many similarities regarding hemodynamic and biochemical parameters. There is evidence that heart failure in experimental animals and humans is accompanied and possibly...
5.
Hofmann B, Kaufmann C, Stiller M, Neitzel T, Wienke A, Silber R, et al.
J Cardiothorac Surg . 2018 May; 13(1):50. PMID: 29784004
Background: Adult cardiac surgery with extracorporeal circulation is known to be associated with increased risk of blood transfusion leading to adverse outcomes. Procedures like retrograde autologous priming (RAP) may reduce...
6.
Jacobs K, Navarrete Santos A, Simm A, Silber R, Hofmann B
Free Radic Biol Med . 2015 Oct; 75 Suppl 1:S34. PMID: 26461346
Advanced glycation end products (AGEs) seem to be involved in ageing as well as in the development of cardiovascular diseases. Accumulation of AGEs contribute to tissue stiffness and organ dysfunction...
7.
Potzsch S, Dalgalarrondo M, Bakan B, Marion D, Somoza V, Stangl G, et al.
Free Radic Biol Med . 2015 Oct; 75 Suppl 1:S19. PMID: 26461302
Objective: Free radicals and oxidative stress are important factors in the biology of aging and responsible for the development of age-related diseases. One way to reduce the formation of free...
8.
Schlitt A, Wischmann P, Wienke A, Hoepfner F, Noack F, Silber R, et al.
Dtsch Arztebl Int . 2015 Sep; 112(31-32):527-34. PMID: 26334980
Background: In Germany, rehabilitation is considered to be indicated after an acute hospital stay for the treatment of a severe cardiac condition. In comparative studies, at least 51% of German...
9.
Simm A, Muller B, Nass N, Hofmann B, Bushnaq H, Silber R, et al.
Exp Gerontol . 2014 Dec; 68:71-5. PMID: 25536383
Unlabelled: Non-enzymatic formation of advanced glycation endproducts (AGEs) is associated with degenerative diseases. Chronic accumulation of AGEs with age in tissues especially in the extracellular matrix is well known and...
10.
Fu H, Spieler F, Grossmann J, Riemann D, Larisch M, Hiebl B, et al.
Atherosclerosis . 2014 Dec; 237(2):443-52. PMID: 25463072
Objectives: Inflammation is essential for atherogenesis. Cholesterol, a cardiovascular risk factor, may activate inflammation in the vessel wall during this process. Cytokine-mediated interactions of human monocytes with vascular smooth muscle...