Roel Goldschmeding
Overview
Explore the profile of Roel Goldschmeding including associated specialties, affiliations and a list of published articles.
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187
Citations
4434
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Recent Articles
1.
Chiu Y, van Dijk M, Goldschmeding R, van Laar J, de Vries-Bouwstra J, Spierings J
Rheumatology (Oxford)
. 2024 Dec;
PMID: 39656818
Objectives: Cellular senescence and endothelial-to-mesenchymal transition (EndMT) are profibrotic cellular processes involved in systemic sclerosis (SSc), but how they respond to treatment is largely unknown. Methods: Skin biopsies from diffuse...
2.
Larsen J, Hegelund J, Pedersen M, Andersson C, Lindegaard C, Hansen D, et al.
Cardiovasc Res
. 2024 Aug;
120(15):1851-1868.
PMID: 39167826
Aims: Cellular communication network factor 2 (CCN2) is a matricellular protein implicated in fibrotic diseases, with ongoing clinical trials evaluating anti-CCN2-based therapies. By uncovering CCN2 as abundantly expressed in non-diseased...
3.
Leguit R, Broekhuizen R, de Witte M, Raymakers R, Goldschmeding R
Virchows Arch
. 2024 Apr;
484(5):837-845.
PMID: 38602559
The classical BCR::ABL1-negative myeloproliferative neoplasms (MPN) form a group of bone marrow (BM) diseases with the potential to progress to acute myeloid leukemia or develop marrow fibrosis and subsequent BM...
4.
Knoppert S, Keijzer-Veen M, Valentijn F, van den Heuvel-Eibrink M, Lilien M, van den Berg G, et al.
J Pathol
. 2023 Oct;
261(4):455-464.
PMID: 37792603
Karyomegalic interstitial nephropathy (KIN) has been reported as an incidental finding in patients with childhood cancer treated with ifosfamide. It is defined by the presence of tubular epithelial cells (TECs)...
5.
Rayego-Mateos S, Marquez-Exposito L, Basantes P, Tejedor-Santamaria L, Sanz A, Nguyen T, et al.
Antioxidants (Basel)
. 2023 Aug;
12(8).
PMID: 37627536
Inflammation is a key characteristic of both acute and chronic kidney diseases. Preclinical data suggest the involvement of the NLRP3/Inflammasome, receptor-interacting protein kinase-3 (RIPK3), and NRF2/oxidative pathways in the regulation...
6.
Chiu Y, Spierings J, van Laar J, de Vries-Bouwstra J, van Dijk M, Goldschmeding R
Clin Exp Rheumatol
. 2023 Jun;
41(8):1612-1617.
PMID: 37382464
Objectives: Fibrosis is the dominant hallmark of systemic sclerosis (SSc). Several mechanisms have been proposed to drive the disease process, but how these relate to skin fibrosis is poorly understood....
7.
Zwart K, Ruigrok D, de Graaf-Bos M, Goldschmeding R, Koopman M, Bol G
Case Rep Transplant
. 2023 Jan;
2023:9643370.
PMID: 36685719
Background: Cancer has become an important cause of death in solid organ transplant patients. The cause of malignancies in patients with solid organ transplants is multifactorial, but the use of...
8.
Knops N, Ramazani Y, de Loor H, Goldschmeding R, Nguyen T, van den Heuvel L, et al.
Nephrol Dial Transplant
. 2022 Aug;
38(3):599-609.
PMID: 35945682
Background: Common genetic variants of the enzymes and efflux pump involved in tacrolimus disposition have been associated with calcineurin inhibitor nephrotoxicity, but their importance is unclear because of the multifactorial...
9.
Valentijn F, Knoppert S, Marquez-Exposito L, Rodrigues-Diez R, Pissas G, Tang J, et al.
Kidney Int
. 2022 Aug;
102(6):1305-1319.
PMID: 35921911
Chronic allograft dysfunction with progressive fibrosis of unknown cause remains a major issue after kidney transplantation, characterized by ischemia-reperfusion injury (IRI). One hypothesis to account for this is that spontaneous...
10.
Cuesta C, Fuentes-Calvo I, Sancho-Martinez S, Valentijn F, Duwel A, Hidalgo-Thomas O, et al.
Biomedicines
. 2022 May;
10(5).
PMID: 35625842
Acute kidney injury (AKI) poses an increased risk factor for new AKI episodes, progression to chronic kidney disease, and death. A worsened evolution has been linked to an incomplete renal...