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Rodrigo Moore-Carrasco

Explore the profile of Rodrigo Moore-Carrasco including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 758
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Recent Articles
1.
Arauna D, Chandia E, Nova-Lamperti E, Radojkovic C, Fuentes E, Palomo I, et al.
Atherosclerosis . 2025 Mar; 403:119119. PMID: 40043445
Background And Aims: Platelets and inflammation play crucial roles in the atherothrombotic process of acute myocardial infarction (AMI), particularly in ischemia/reperfusion injury. This study aims to characterize the pro-inflammatory content...
2.
Valero P, Silva K, Valenzuela-Hinrichsen A, Vasquez A, Espinoza F, Lira F, et al.
J Physiol . 2024 Oct; PMID: 39470472
Extracellular vesicles (EVs) play a crucial role in mediating communication between cells across species and kingdoms. The intercellular communication facilitated by EVs through autocrine and paracrine signalling mechanisms is essential...
3.
Cayo A, Venturini W, Rebolledo-Mira D, Moore-Carrasco R, Herrada A, Nova-Lamperti E, et al.
Int J Mol Sci . 2023 Jun; 24(11). PMID: 37298236
Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the senescence-associated secretory phenotype (SASP). In addition, senescent cells...
4.
Valero P, Cornejo M, Fuentes G, Wehinger S, Toledo F, van der Beek E, et al.
Acta Physiol (Oxf) . 2023 Jan; 237(4):e13940. PMID: 36700365
The prevalence of gestational diabetes mellitus (GDM) has increased in recent years, along with the higher prevalence of obesity in women of reproductive age. GDM is a pathology associated with...
5.
Huilcaman R, Venturini W, Fuenzalida L, Cayo A, Segovia R, Valenzuela C, et al.
Cells . 2022 Mar; 11(6). PMID: 35326465
Platelets play important roles in thrombosis-dependent obstructive cardiovascular diseases. In addition, it has now become evident that platelets also participate in the earliest stages of atherosclerosis, including the genesis of...
6.
Cayo A, Segovia R, Venturini W, Moore-Carrasco R, Valenzuela C, Brown N
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360912
Cellular senescence is a form of proliferative arrest triggered in response to a wide variety of stimuli and characterized by unique changes in cell morphology and function. Although unable to...
7.
Cornejo M, Fuentes G, Valero P, Vega S, Grismaldo A, Toledo F, et al.
Acta Physiol (Oxf) . 2021 May; 232(4):e13671. PMID: 33942517
Gestational diabetes mellitus (GDM) shows a deficiency in the metabolism of D-glucose and other nutrients, thereby negatively affecting the foetoplacental vascular endothelium. Maternal hyperglycaemia and hyperinsulinemia play an important role...
8.
Huilcaman R, Veliz-Olivos N, Venturini W, Olate-Briones A, Treuer A, Valenzuela C, et al.
Platelets . 2021 Mar; 32(8):1113-1119. PMID: 33775219
Cardiovascular diseases (CVDs) remain leading causes of death worldwide. While platelet-mediated thrombus formation following the rupture of an atherosclerotic plaque is one of the key pathophysiologic events in CVDs, the...
9.
Venturini W, Olate-Briones A, Valenzuela C, Mendez D, Fuentes E, Cayo A, et al.
Int J Mol Sci . 2020 May; 21(9). PMID: 32384773
Aging is one of the main risk factors for the development of chronic diseases, with both the vascular endothelium and platelets becoming functionally altered. Cellular senescence is a form of...
10.
Valenzuela C, Quintanilla R, Olate-Briones A, Venturini W, Mancilla D, Cayo A, et al.
Int J Mol Sci . 2019 Oct; 20(21). PMID: 31653055
Alterations in platelet aggregation are common in aging individuals and in the context of age-related pathologies such as cancer. So far, however, the effects of senescent cells on platelets have...