Rodrigo G de Souza
Overview
Explore the profile of Rodrigo G de Souza including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
234
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Recent Articles
1.
Trujillo-Vargas C, Mauk K, Hernandez H, de Souza R, Yu Z, Galletti J, et al.
Geroscience
. 2022 Mar;
44(4):2105-2128.
PMID: 35279788
Aging is associated with a massive infiltration of T lymphocytes in the lacrimal gland. Here, we aimed to characterize the immune phenotype of aged CD4 T cells in this tissue...
2.
Trujillo-Vargas C, Kutlehria S, Hernandez H, de Souza R, Lee A, Yu Z, et al.
Int J Mol Sci
. 2020 Dec;
21(23).
PMID: 33255287
Dry eye disease (DED), one of the most prevalent conditions among the elderly, is a chronic inflammatory disorder that disrupts tear film stability and causes ocular surface damage. Aged C57BL/6J...
3.
de Souza R, Yu Z, Hernandez H, Trujillo-Vargas C, Lee A, Mauk K, et al.
Am J Pathol
. 2020 Nov;
191(2):294-308.
PMID: 33159886
Inflammation and oxidative stress accompany aging. This study investigated the interplay between oxidative stress and inflammation in the lacrimal gland. C57BL/6 mice were used at 2 to 3, 12, and...
4.
Alam J, de Souza R, Yu Z, Stern M, de Paiva C, Pflugfelder S
J Ocul Pharmacol Ther
. 2020 Jul;
36(9):679-685.
PMID: 32721249
The purpose of this study was to evaluate the potential of voclosporin (VOS) in preventing goblet cell (GC) loss and modulating interferon-gamma (IFN-γ) producing CD4 T cells in the mouse...
5.
Wang L, Spektor T, de Souza R, Koch D
J Cataract Refract Surg
. 2019 Aug;
45(10):1416-1421.
PMID: 31399324
Purpose: To compare the accuracy of total keratometry (TK) and standard keratometry (K) from a swept-source optical coherence tomography biometer for intraocular lens (IOL) power calculation in eyes with previous...
6.
Deng R, Chen X, Zhang Y, Bian F, Gao N, Hu J, et al.
Mucosal Immunol
. 2019 Jul;
12(5):1141-1149.
PMID: 31350466
This study was to explore the role and mechanism of macrophages in pollen-triggered allergic inflammation. A murine model of short ragweed (SRW) pollen-induced experimental allergic conjunctivitis (EAC), and bone marrow...
7.
de Souza R, de Paiva C, Alves M
Immune Netw
. 2019 Mar;
19(1):e3.
PMID: 30838158
Aging is a complex process associated with dysregulation of the immune system and low levels of inflammation, often associated with the onset of many pathologies. The lacrimal gland (LG) plays...
8.
Bian F, Xiao Y, Barbosa F, de Souza R, Hernandez H, Yu Z, et al.
Mucosal Immunol
. 2019 Jan;
12(4):897-908.
PMID: 30696983
Aging is a significant risk factor for dry eye. Here we used a murine aging model to investigate the effects of aging on antigen presenting cells (APCs) and generation of...
9.
Xiao Y, de Paiva C, Yu Z, de Souza R, Li D, Pflugfelder S
Int Immunol
. 2018 Jul;
30(10):457-470.
PMID: 30010888
Conjunctival goblet cell loss in ocular surface diseases is accompanied by increased number of interleukin-12 (IL-12)-producing antigen-presenting cells (APCs) and increased interferon-γ (IFN-γ) expression. This study tested the hypothesis that...
10.
Zaheer M, Wang C, Bian F, Yu Z, Hernandez H, de Souza R, et al.
J Autoimmun
. 2018 Jun;
93:45-56.
PMID: 29934134
CD25 knock-out (CD25KO) mice spontaneously develop Sjögren Syndrome (SS)-like inflammation. We investigated the role of commensal bacteria by comparing CD25KO mice housed in conventional or germ-free conditions. Germ-free CD25KO mice...