Rodney A Lea
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Explore the profile of Rodney A Lea including associated specialties, affiliations and a list of published articles.
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70
Citations
874
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Recent Articles
1.
Arunachalam V, Tran K, Hoy W, Lea R, Nagaraj S
Eur J Hum Genet
. 2025 Feb;
PMID: 39994404
The genetic distinctiveness of Indigenous Australian populations is well established, yet the Tiwi population remains underrepresented in genetic research. Due to their prolonged geographic isolation, these populations are prone to...
2.
Alfayyadh M, Maksemous N, Sutherland H, Lea R, Griffiths L
Clin Genet
. 2024 Oct;
107(2):157-168.
PMID: 39394929
The exponential growth of next-generation sequencing (NGS) data requires innovative bioinformatics approaches to unravel the genetic underpinnings of diseases. Hemiplegic migraine (HM), a debilitating neurological disorder with a genetic basis,...
3.
Binder M, Nwoke E, Morwitch E, Dwyer C, Li V, Xavier A, et al.
Neurol Neuroimmunol Neuroinflamm
. 2023 Dec;
11(2):e200190.
PMID: 38150649
Background And Objectives: HLA-DRB1*15:01 (DR15) and are 2 risk genes for multiple sclerosis (MS). The variant rs7422195 is an expression quantitative trait locus for MERTK in CD14 monocytes; cells with...
4.
Temperley I, Seldon A, Reckord M, Yarad C, Islam F, Duncanson K, et al.
Mult Scler J Exp Transl Clin
. 2023 Dec;
9(4):20552173231218107.
PMID: 38130338
Background: Many diets promoted specifically for multiple sclerosis have been suggested to improve disease activity. Dairy and gluten are two components for which the recommendations vary between these diets. Existing...
5.
Amin M, Al-Iedani O, Lea R, Brilot F, Maltby V, Lechner-Scott J
J Neuroimaging
. 2023 Nov;
34(1):78-85.
PMID: 38018386
Background And Purpose: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a relapsing demyelinating condition. There are several cross-sectional studies showing evidence of brain atrophy in people with MOGAD (pwMOGAD), but...
6.
Cao T, Sutherland H, Benton M, Haupt L, Lea R, Griffiths L
Curr Issues Mol Biol
. 2023 Oct;
45(10):7862-7877.
PMID: 37886940
DNA methylation is an epigenetic factor that is modifiable and can change over a lifespan. While many studies have identified methylation sites (CpGs) related to aging, the relationship of these...
7.
OBrien S, Lea R, Jadhao S, Lee S, Sukhadia S, Arunachalam V, et al.
Genes (Basel)
. 2023 Sep;
14(9).
PMID: 37761880
Improvements in blood group genotyping methods have allowed large scale population-based blood group genetics studies, facilitating the discovery of rare blood group antigens. Norfolk Island, an external and isolated territory...
8.
Xavier A, Maltby V, Ewing E, Campagna M, Burnard S, Tegner J, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628757
Epigenetic mechanisms can regulate how DNA is expressed independently of sequence and are known to be associated with various diseases. Among those epigenetic mechanisms, DNA methylation (DNAm) is influenced by...
9.
Dunn P, Lea R, Maksemous N, Smith R, Sutherland H, Haupt L, et al.
Hum Genet
. 2023 Jul;
142(9):1361-1373.
PMID: 37422595
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a condition caused by mutations in NOTCH3 and results in a phenotype characterised by recurrent strokes, vascular dementia and...
10.
Campagna M, Lechner-Scott J, Maltby V, Lea R, Butzkueven H, Jokubaitis V
Autoimmun Rev
. 2023 Jun;
22(9):103388.
PMID: 37352902
Multiple sclerosis (MS) is an autoimmune, demyelinating disease with the highest incidence in women of childbearing age. The effect of pregnancy on disease activity and progression is a primary concern...