Rodell C Barrientos
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Explore the profile of Rodell C Barrientos including associated specialties, affiliations and a list of published articles.
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23
Citations
116
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Recent Articles
1.
Arcinas A, Larson E, Buchhalter E, Dunn Z, Wang H, Singh A, et al.
J Chromatogr A
. 2025 Mar;
1748:465851.
PMID: 40086145
The quantitation of the major capsid protein L1 is an important metric during the pharmaceutical manufacturing of human papilloma virus (HPV) vaccines, as they are critical components of virus like...
2.
DAtri V, Barrientos R, Losacco G, Rudaz S, Delobel A, Regalado E, et al.
Anal Chem
. 2025 Feb;
97(9):4706-4727.
PMID: 40008977
No abstract available.
3.
Hemida M, Barrientos R, Kinsey C, Kuster N, Bhavsar M, Beck A, et al.
ACS Pharmacol Transl Sci
. 2024 Oct;
7(10):3108-3118.
PMID: 39421659
The growing use of adjuvants in the fast-paced formulation of new vaccines has created an unprecedented need for meaningful analytical assays that deliver reliable quantitative data from complex adjuvant and...
4.
Hemida M, Barrientos R, Singh A, Losacco G, Wang H, Guillarme D, et al.
J Chromatogr A
. 2024 Aug;
1733:465266.
PMID: 39163703
The pharmaceutical industry is rapidly advancing toward new drug modalities, necessitating the development of advanced analytical strategies for effective, meaningful, and reliable assays. Hydrophilic Interaction Chromatography (HILIC) is a powerful...
5.
Dunham N, Winston M, Ray R, Eberle C, Newman J, Gao Q, et al.
J Am Chem Soc
. 2024 May;
146(23):16306-16313.
PMID: 38804633
Transaminases are choice biocatalysts for the synthesis of chiral primary amines, including amino acids bearing contiguous stereocenters. In this study, we employ lysine as a "smart" amine donor in transaminase-catalyzed...
6.
Naser Aldine F, Singh A, Wang H, Makey D, Barrientos R, Wong M, et al.
J Chromatogr A
. 2024 Apr;
1722:464830.
PMID: 38608366
Development of meaningful and reliable analytical assays in the (bio)pharmaceutical industry can often be challenging, involving tedious trial and error experimentation. In this work, an automated analytical workflow using an...
7.
Barrientos R, Singh A, Ukaegbu O, Hemida M, Wang H, Haidar Ahmad I, et al.
Anal Chem
. 2024 Mar;
96(12):4960-4968.
PMID: 38436624
The emergence of complex biological modalities in the biopharmaceutical industry entails a significant expansion of the current analytical toolbox to address the need to deploy meaningful and reliable assays at...
8.
Hemida M, Haidar Ahmad I, Barrientos R, Regalado E
Anal Chim Acta
. 2024 Feb;
1293:342178.
PMID: 38331548
The (bio)pharmaceutical industry is rapidly moving towards complex drug modalities that require a commensurate level of analytical enabling technologies that can be deployed at a fast pace. Unsystematic method development...
9.
Abucayon E, Barrientos R, Torres O, Sweeney S, Whalen C, Matyas G
ACS Omega
. 2023 Jun;
8(23):21016-21025.
PMID: 37323401
Identification and quantification of an active adjuvant and its degradation product/s in drug formulations are important to ensure drug product safety and efficacy. QS-21 is a potent adjuvant that is...
10.
Barrientos R, Losacco G, Azizi M, Wang H, Nguyen A, Shchurik V, et al.
Anal Chem
. 2022 Nov;
94(49):17131-17141.
PMID: 36441925
The mounting complexity of new modalities in the biopharmaceutical industry entails a commensurate level of analytical innovations to enable the rapid discovery and development of novel therapeutics and vaccines. Hydrophobic...