Robin Canac
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Explore the profile of Robin Canac including associated specialties, affiliations and a list of published articles.
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9
Citations
29
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Recent Articles
1.
Ansari S, Dillard M, Ghonim M, Zhang Y, Stewart D, Canac R, et al.
bioRxiv
. 2025 Feb;
PMID: 39975106
Sonic Hedgehog (SHH) signaling functions in temporal- and context-dependent manners to pattern diverse tissues during embryogenesis. The signal transducer Smoothened (SMO) is activated by sterols, oxysterols, and arachidonic acid (AA)...
2.
Geryk M, Canac R, Forest V, Lindenbaum P, Girardeau A, Baudic M, et al.
Stem Cell Res
. 2024 Mar;
77:103396.
PMID: 38522388
Mutations in the DES gene, which encodes the intermediate filament desmin, lead to desminopathy, a rare disease characterized by skeletal muscle weakness and different forms of cardiomyopathies associated with cardiac...
3.
Canac R, Cimarosti B, Girardeau A, Forest V, Olchesqui P, Poschmann J, et al.
Cells
. 2022 Dec;
11(23).
PMID: 36497174
Human heart development is governed by transcription factor (TF) networks controlling dynamic and temporal gene expression alterations. Therefore, to comprehensively characterize these transcriptional regulations, day-to-day transcriptomic profiles were generated throughout...
4.
Caillaud A, Leveque A, Thedrez A, Girardeau A, Canac R, Bray L, et al.
STAR Protoc
. 2022 Sep;
3(4):101680.
PMID: 36115027
This manuscript proposes an efficient and reproducible protocol for the generation of genetically modified human induced pluripotent stem cells (hiPSCs) by genome editing using CRISPR-Cas9 technology. Here, we describe the...
5.
Cimarosti B, Canac R, De Waard S, Girardeau A, Gaignerie A, Derevier A, et al.
Stem Cell Res
. 2022 Feb;
60:102688.
PMID: 35101670
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is an exercise and emotional stress-induced life-threatening inherited heart rhythm disorder, characterized by an abnormal cellular calcium homeostasis. Most reported cases have been linked to...
6.
Girardeau A, Atticus D, Canac R, Cimarosti B, Caillaud A, Chariau C, et al.
Stem Cell Res
. 2022 Jan;
59:102647.
PMID: 34999420
Four human induced pluripotent stem cell (hiPSC) lines have been generated from healthy control European donors, and validated. This resource represents a useful tool for stem cell-based research, as references...
7.
Cimarosti B, Canac R, Girardeau A, Arnaud M, Francheteau Q, Probst V, et al.
Stem Cell Res
. 2022 Jan;
59:102649.
PMID: 34995842
Catecholamine-induced QT prolongation (CIQTP) is an inherited cardiac disease characterized by a normal baseline ECG and a risk of sudden cardiac death by ventricular arrhythmia due to a QT prolongation...
8.
Canac R, Caillaud A, Cimarosti B, Girardeau A, Hamamy H, Reversade B, et al.
Stem Cell Res
. 2021 Dec;
58:102627.
PMID: 34929443
Studies on animal models have shown that Irx5 is an important regulator of cardiac development and that it regulates ventricular electrical repolarization gradient in the adult heart. Mutations in IRX5...
9.
Al Sayed Z, Jouni M, Gourraud J, Belbachir N, Barc J, Girardeau A, et al.
Clin Transl Med
. 2021 Jun;
11(6):e413.
PMID: 34185406
No abstract available.
10.
Al Sayed Z, Canac R, Cimarosti B, Bonnard C, Gourraud J, Hamamy H, et al.
Cardiovasc Res
. 2020 Sep;
117(9):2092-2107.
PMID: 32898233
Aims: Several inherited arrhythmic diseases have been linked to single gene mutations in cardiac ion channels and interacting proteins. However, the mechanisms underlying most arrhythmias, are thought to involve altered...