Roberto Marotta
Overview
Explore the profile of Roberto Marotta including associated specialties, affiliations and a list of published articles.
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Articles
75
Citations
1006
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0
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Recent Articles
1.
Chiarugi S, Margheriti F, De Lorenzi V, Martino E, Margheritis E, Moscardini A, et al.
Cell Chem Biol
. 2025 Feb;
PMID: 39999832
Thiazide and thiazide-like diuretics are among the most efficacious and used drugs for the treatment of hypertension, edema, and major cardiovascular outcomes. Despite more then than six decades of clinical...
2.
Valentino V, De Filippis F, Marotta R, Pasolli E, Ercolini D
Cell Rep
. 2024 Nov;
43(12):115018.
PMID: 39615045
The genus Ruminococcus is dominant in the human gut, but higher levels of some species, such as R. gnavus, R. torques, and R. bromii, have been linked to health or...
3.
Montemurro N, Zotti N, Guercini J, De Carolis G, Leoni C, Marotta R, et al.
Surg Neurol Int
. 2024 Oct;
15:348.
PMID: 39373005
Background: Chronic back pain stands as the most common musculoskeletal disorder and a primary cause of disability in people under 45 years old. Multidisciplinary consultation offers an efficient approach to...
4.
Balboni B, Marotta R, Rinaldi F, Milordini G, Varignani G, Girotto S, et al.
Commun Biol
. 2024 Aug;
7(1):956.
PMID: 39112549
Human RAD52 (RAD52) is a DNA-binding protein involved in many DNA repair mechanisms and genomic stability maintenance. In the last few years, this protein was discovered to be a promising...
5.
Carretta A, Moscardini A, Signore G, Debellis D, Catalano F, Marotta R, et al.
Mol Ther Oncol
. 2024 Jul;
32(3):200836.
PMID: 39050990
The successful trajectory of liposome-encapsulated doxorubicin (e.g., Doxil, which has been approved by the U.S. Food and Drug Administration) as an anticancer nanodrug in clinical applications is contradicted by cell...
6.
Schlich M, DApice L, Lai F, Sinico C, Valenti D, Catalano F, et al.
Int J Pharm
. 2024 Jun;
661:124404.
PMID: 38945464
Vaccines based on protein antigens have numerous advantages over inactivated pathogens, including easier manufacturing and improved safety. However, purified antigens are weakly immunogenic, as they lack the spatial organization and...
7.
Pitchaimani A, Ferreira M, Palange A, Pannuzzo M, De Mei C, Spano R, et al.
Nanoscale Adv
. 2023 Dec;
5(24):6830-6836.
PMID: 38059035
In the development of therapeutic extracellular vesicles (EVs), drug encapsulation efficiencies are significantly lower when compared with synthetic nanomedicines. This is due to the hierarchical structure of the EV membrane...
8.
Rinaldi F, Schipani F, Balboni B, Catalano F, Marotta R, Myers S, et al.
Angew Chem Int Ed Engl
. 2023 Nov;
62(51):e202312517.
PMID: 37924230
DNA repair protein RAD51 is a key player in the homologous recombination pathway. Upon DNA damage, RAD51 is transported into the nucleus by BRCA2, where it can repair DNA double-strand...
9.
Rosito M, Sanchini C, Gosti G, Moreno M, De Panfilis S, Giubettini M, et al.
Cell Rep
. 2023 Feb;
42(2):112104.
PMID: 36787220
Microglia reactivity entails a large-scale remodeling of cellular geometry, but the behavior of the microtubule cytoskeleton during these changes remains unexplored. Here we show that activated microglia provide an example...
10.
Morillas-Becerril L, Franco-Ulloa S, Fortunati I, Marotta R, Sun X, Zanoni G, et al.
Commun Chem
. 2023 Jan;
4(1):93.
PMID: 36697571
Understanding and controlling the interaction between nanoparticles and biological entities is fundamental to the development of nanomedicine applications. In particular, the possibility to realize nanoparticles capable of directly targeting neutral...