Roberto de Pasquale
Overview
Explore the profile of Roberto de Pasquale including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
1370
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Recent Articles
1.
Juvenal G, Higa G, Bonfim Marques L, Tessari Zampieri T, Viana F, Britto L, et al.
Purinergic Signal
. 2024 Jul;
PMID: 39046648
Purinergic receptors regulate the processing of neural information in the hippocampus and cerebral cortex, structures related to cognitive functions. These receptors are activated when astrocytic and neuronal populations release adenosine...
2.
Higa G, Viana F, Francis-Oliveira J, Cruvinel E, Franchin T, Marcourakis T, et al.
Neuropharmacology
. 2024 Jun;
257:110036.
PMID: 38876308
Synaptic plasticity constitutes a fundamental process in the reorganization of neural networks that underlie memory, cognition, emotional responses, and behavioral planning. At the core of this phenomenon lie Hebbian mechanisms,...
3.
Carlos-Lima E, Higa G, Viana F, Tamais A, Cruvinel E, Borges F, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203689
Serotonergic neurons constitute one of the main systems of neuromodulators, whose diffuse projections regulate the functions of the cerebral cortex. Serotonin (5-HT) is known to play a crucial role in...
4.
Francis-Oliveira J, Higa G, Viana F, Cruvinel E, Carlos-Lima E, Borges F, et al.
Exp Neurol
. 2023 Dec;
373:114652.
PMID: 38103709
Synaptic plasticity is one of the putative mechanisms involved in the maturation of the prefrontal cortex (PFC) during postnatal development. Early life stress (ELS) affects the shaping of cortical circuitries...
5.
Higa G, Francis-Oliveira J, Carlos-Lima E, Tamais A, Borges F, Kihara A, et al.
Sci Rep
. 2022 Dec;
12(1):21015.
PMID: 36470912
Important functions of the prefrontal cortex (PFC) are established during early life, when neurons exhibit enhanced synaptic plasticity and synaptogenesis. This developmental stage drives the organization of cortical connectivity, responsible...
6.
Marinho L, Chiarantin G, Ikebara J, Cardoso D, de Lima-Vasconcellos T, Higa G, et al.
Semin Cell Dev Biol
. 2022 Sep;
144:67-76.
PMID: 36115764
The use of antidepressants during pregnancy benefits the mother's well-being, but the effects of such substances on neurodevelopment remain poorly understood. Moreover, the consequences of early exposure to antidepressants may...
7.
Vitureira N, de Pasquale R, Leao R, Rossi F
Front Cell Neurosci
. 2022 Aug;
16:980623.
PMID: 35910252
No abstract available.
8.
Metaplasticity in the Visual Cortex: Crosstalk Between Visual Experience and Reactive Oxygen Species
Francis-Oliveira J, Vilar Higa G, Dati L, Shieh I, de Pasquale R
J Neurosci
. 2018 May;
38(25):5649-5665.
PMID: 29789380
Metaplasticity is the regulation of synaptic plasticity based on the history of previous synaptic activation. This concept was formulated after observing that synaptic changes in the visual cortex are not...
9.
Bridi M, de Pasquale R, Lantz C, Gu Y, Borrell A, Choi S, et al.
Nat Neurosci
. 2018 May;
21(6):843-850.
PMID: 29760525
Models of firing rate homeostasis such as synaptic scaling and the sliding synaptic plasticity modification threshold predict that decreasing neuronal activity (for example, by sensory deprivation) will enhance synaptic function....
10.
Beckhauser T, Francis-Oliveira J, de Pasquale R
J Exp Neurosci
. 2016 Sep;
10(Suppl 1):23-48.
PMID: 27625575
In the mammalian central nervous system, reactive oxygen species (ROS) generation is counterbalanced by antioxidant defenses. When large amounts of ROS accumulate, antioxidant mechanisms become overwhelmed and oxidative cellular stress...