Roberto Crackel
Overview
Explore the profile of Roberto Crackel including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
6
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0
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Recent Articles
1.
Wang Y, Tu W, Koh W, Travis J, Abugov R, Hamilton K, et al.
Pharm Stat
. 2024 Jul;
23(6):1065-1083.
PMID: 39010686
In conventional subgroup analyses, subgroup treatment effects are estimated using data from each subgroup separately without considering data from other subgroups in the same study. The subgroup treatment effects estimated...
2.
Wang Y, Tu W, Kim Y, Sinks S, He J, Cambon A, et al.
Pharm Stat
. 2023 Mar;
22(4):650-670.
PMID: 36970810
The International Council for Harmonization (ICH) E9(R1) addendum recommends choosing an appropriate estimand based on the study objectives in advance of trial design. One defining attribute of an estimand is...
3.
He J, Crackel R, Koh W, Chen L, Li F, Zhang J, et al.
J Biopharm Stat
. 2022 Sep;
33(2):234-252.
PMID: 36121193
Recently, retrieved-dropout-based multiple imputation has been used in some therapeutic areas to address the treatment policy estimand, mostly for continuous endpoints. In this approach, data from subjects who discontinued study...