Roberta Foresti
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Explore the profile of Roberta Foresti including associated specialties, affiliations and a list of published articles.
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82
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3194
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Recent Articles
1.
Giuffrida E, Platania C, Lazzara F, Conti F, Sotera L, Drago F, et al.
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940746
Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus and a leading cause of blindness in the working-age population. Current pharmacological treatments counteract DR's later stages without targeting the...
2.
Stegnjaic G, Nikolovski N, Stanisavljevic S, Lazarevic M, Momcilovic M, Foresti R, et al.
Clin Exp Immunol
. 2024 Nov;
219(1).
PMID: 39540912
HYCOs are hybrid molecules consisting of activators of the transcription factor Nrf2 conjugated to carbon monoxide (CO)-releasing moieties. These 'dual action' compounds (HYCOs) have been designed to mimic the activity...
3.
Pradhan P, Vijayan V, Liu B, Martinez-Delgado B, Matamala N, Nikolin C, et al.
Redox Biol
. 2024 May;
73:103191.
PMID: 38762951
Activation of inflammation is tightly associated with metabolic reprogramming in macrophages. The iron-containing tetrapyrrole heme can induce pro-oxidant and pro-inflammatory effects in murine macrophages, but has been associated with polarization...
4.
Morgenstern C, Lastres-Becker I, Demirdogen B, Costa V, Daiber A, Foresti R, et al.
Redox Biol
. 2024 Apr;
72:103134.
PMID: 38643749
The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a number of diseases associated with oxidative stress...
5.
Benrahla D, Mohan S, Trickovic M, Castelli F, Alloul G, Sobngwi A, et al.
Redox Biol
. 2024 Apr;
72:103153.
PMID: 38608580
Carbon monoxide (CO), a gaseous signaling molecule, has shown promise in preventing body weight gain and metabolic dysfunction induced by high fat diet (HFD), but the mechanisms underlying these effects...
6.
Nguyen K, Matte A, Foresti R, Federti E, Kiger L, Lefebvre C, et al.
Blood
. 2024 Mar;
143(24):2544-2558.
PMID: 38518106
Acute hyperhemolysis is a severe life-threatening complication in patients with sickle cell disease (SCD) that may occur during delayed hemolytic transfusion reaction (DHTR), or vaso-occlusive crises associated with multiorgan failure....
7.
Nekooie Marnany N, Fodil R, Fereol S, Dady A, Depp M, Relaix F, et al.
J Cell Sci
. 2023 Aug;
136(16).
PMID: 37589341
Bioenergetic metabolism is a key regulator of cellular function and signaling, but how it can instruct the behavior of cells and their fate during embryonic development remains largely unknown. Here,...
8.
Herath D, Even B, Oranger M, Foresti R, Papy D, Boyer L, et al.
Free Radic Biol Med
. 2023 May;
205:129-140.
PMID: 37257701
Rationale: Lung fibroblast senescence is involved in the pathophysiology of chronic obstructive pulmonary disease (COPD). However, the mechanisms underlining this phenomenon are still poorly understood. Secreted phospholipases (sPLA2, a subclass...
9.
Mohan S, Barel L, Benrahla D, Do B, Mao Q, Kitagishi H, et al.
Pharmacol Res
. 2023 Apr;
191:106770.
PMID: 37068532
Metal carbonyls have been developed as carbon monoxide-releasing molecules (CO-RMs) to deliver CO for therapeutic purposes. The manganese-based CORM-401 has been recently reported to exert beneficial effects in obese animals...
10.
Mao Q, Zhao X, Kiriyama A, Negi S, Fukuda Y, Yoshioka H, et al.
Proc Natl Acad Sci U S A
. 2023 Feb;
120(9):e2209924120.
PMID: 36802431
Simultaneous poisoning by carbon monoxide (CO) and hydrogen cyanide is the major cause of mortality in fire gas accidents. Here, we report on the invention of an injectable antidote against...