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Roberta Figueiroa Souza

Explore the profile of Roberta Figueiroa Souza including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 43
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Recent Articles
1.
Souza R, Machado F, Caetano M, De Paulo C, Castelucci P
Dig Dis Sci . 2025 Feb; PMID: 39946069
Background: Inflammatory bowel diseases (IBD) affect both enteric neurons and enteric glia, with tumor necrosis factor-alpha (TNF-α) playing a role as an inflammatory mediator. Aims: Analyze the effects of the...
2.
Pereira T, Mendes C, Souza R, Caetano M, Magalhaes H, De Paulo C, et al.
Neurogastroenterol Motil . 2025 Jan; :e14996. PMID: 39758008
Background: Intestinal ischemia affects the functioning of the Enteric Nervous System (ENS). Pannexin-1 channel participates in cell communication and extracellular signaling. Probenecid (PB) is a pannexin-1 channel inhibitor, which can...
3.
Magalhaes H, Machado F, Souza R, Caetano M, Figliuolo V, Coutinho-Silva R, et al.
World J Gastroenterol . 2023 Jun; 29(22):3440-3468. PMID: 37389242
Background: The literature indicates that the enteric nervous system is affected in inflammatory bowel diseases (IBDs) and that the P2X7 receptor triggers neuronal death. However, the mechanism by which enteric...
4.
Machado F, Souza R, Figliuolo V, Coutinho-Silva R, Castelucci P
Histochem Cell Biol . 2023 Jun; 160(4):321-339. PMID: 37306742
This study aimed to investigate the distal colon myenteric plexus and enteric glial cells (EGCs) in P2X7 receptor-deficient (P2X7-/-) animals after the induction of experimental ulcerative colitis. 2,4,6-Trinitrobenzene sulfonic acid...
5.
Souza R, Caetano M, Magalhaes H, Castelucci P
World J Gastroenterol . 2023 Jun; 29(18):2733-2746. PMID: 37274062
Ulcerative colitis (UC) and Crohn's disease (CD) are part of Inflammatory Bowel Diseases (IBD) and have pathophysiological processes such as bowel necrosis and enteric neurons and enteric glial cells. In...
6.
Evangelinellis M, Souza R, Mendes C, Castelucci P
Histochem Cell Biol . 2021 Oct; 157(1):65-81. PMID: 34626216
Inflammatory bowel diseases (IBDs) are chronic diseases of the gastrointestinal tract that include ulcerative colitis and Crohn's disease and affect enteric neurons. Research has shown that Brilliant Blue G (BBG),...
7.
Souza R, Evangelinellis M, Mendes C, Righetti M, Lourenco M, Castelucci P
World J Gastrointest Pathophysiol . 2020 Jun; 11(4):84-103. PMID: 32587788
Background: The P2X7 receptor is expressed by enteric neurons and enteric glial cells. Studies have demonstrated that administration of a P2X7 receptor antagonist, brilliant blue G (BBG), prevents neuronal loss....