Roberta Di Benedetto
Overview
Explore the profile of Roberta Di Benedetto including associated specialties, affiliations and a list of published articles.
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23
Citations
769
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Recent Articles
1.
Di Benedetto R, Massai L, Wright M, Mancini F, Cleveland M, Rossi O, et al.
Int J Mol Sci
. 2024 Nov;
25(21).
PMID: 39519015
Alum is the most used vaccine adjuvant, due to its safety, low cost and adjuvanticity to various antigens. However, the mechanism of action of alum is complex and not yet...
2.
Nappini R, Alfini R, Durante S, Salvini L, Raso M, Palmieri E, et al.
Vaccines (Basel)
. 2024 Jul;
12(7).
PMID: 39066345
Glycoconjugation is a well-established technology for vaccine development: linkage of the polysaccharide (PS) antigen to an appropriate carrier protein overcomes the limitations of PS T-independent antigens, making them effective in...
3.
Nonne F, Molfetta M, Nappini R, La Guidara C, Di Benedetto R, Mfana S, et al.
Biology (Basel)
. 2024 Apr;
13(4).
PMID: 38666868
(Kp) is a Gram-negative bacterium, and a leading cause of neonatal sepsis in low- and middle-income countries, often associated with anti-microbial resistance. Two types of polysaccharides are expressed on the...
4.
Oldrini D, Di Benedetto R, Carducci M, De Simone D, Massai L, Alfini R, et al.
Vaccines (Basel)
. 2023 Dec;
11(12).
PMID: 38140177
Glycoconjugate vaccines play a major role in the prevention of infectious diseases worldwide, with significant impact on global health, enabling the polysaccharides to induce immunogenicity in infants and immunological memory....
5.
Di Benedetto R, Mancini F, Caradonna V, Aruta M, Giannelli C, Rossi O, et al.
Front Mol Biosci
. 2023 Dec;
10:1284515.
PMID: 38046812
Shigellosis is leading bacterial cause of diarrhea with high prevalence in children younger than 5 years in low- and middle-income countries, and increasing number of reports of cases associated to...
6.
Piccioli D, Buricchi F, Bacconi M, Bechi N, Galli B, Ferlicca F, et al.
Vaccines (Basel)
. 2023 Jul;
11(7).
PMID: 37515035
Generalized Modules for Membrane Antigens (GMMA) are outer membrane vesicles derived from Gram-negative bacteria that can be used to design affordable subunit vaccines. GMMA have been observed to induce a...
7.
Jossi S, Arcuri M, Alshayea A, Persaud R, Marcial-Juarez E, Palmieri E, et al.
Front Immunol
. 2023 Apr;
14:1139329.
PMID: 37033932
Introduction: Vaccination with Vi capsular polysaccharide (Vi-PS) or protein-Vi typhoid conjugate vaccine (TCV) can protect adults against Typhi infections. TCVs offer better protection than Vi-PS in infants and may offer...
8.
Pitirollo O, Di Benedetto R, Henriques P, Gasperini G, Mancini F, Carducci M, et al.
Carbohydr Polym
. 2023 Apr;
311:120736.
PMID: 37028871
Group A Carbohydrate (GAC), conjugated to an appropriate carrier protein, has been proposed as an attractive vaccine candidate against Group A Streptococcus infections. Native GAC consists of a polyrhamnose (polyRha)...
9.
Palmieri E, Kis Z, Ozanne J, Di Benedetto R, Ricchetti B, Massai L, et al.
Vaccines (Basel)
. 2022 Jul;
10(7).
PMID: 35891202
Group A (GAS) causes about 500,000 annual deaths globally, and no vaccines are currently available. The Group A Carbohydrate (GAC), conserved across all GAS serotypes, conjugated to an appropriate carrier...
10.
Di Benedetto R, Alfini R, Carducci M, Aruta M, Lanzilao L, Acquaviva A, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638530
Outer Membrane Vesicles (OMV) constitute a promising platform for the development of efficient vaccines. OMV can be decorated with heterologous antigens (proteins or polysaccharides), becoming attractive novel carriers for the...