Robert T Naismith
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Explore the profile of Robert T Naismith including associated specialties, affiliations and a list of published articles.
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107
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2122
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Recent Articles
1.
Shelley N, Judge B, Yablonskiy D, Naismith R, Brier M, Cross A
Ann Clin Transl Neurol
. 2025 Mar;
PMID: 40080404
Objective: The claustrum is a small, thin structure of predominantly gray matter with broad connectivity and enigmatic function. Little is known regarding the impact of claustrum pathology in multiple sclerosis...
2.
Conway D, Nicholas J, Thompson N, Mowry E, Naismith R
Mult Scler Relat Disord
. 2025 Jan;
94:106272.
PMID: 39827538
Background: Cladribine tablets (CladT) are a multiple sclerosis (MS) disease-modifying therapy (DMT) with safety and efficacy established in the CLARITY trial and extension. A better understanding of the role of...
3.
Brier M, Judge B, Ying C, Salter A, An H, Patel A, et al.
Ann Neurol
. 2024 Dec;
97(4):766-778.
PMID: 39714123
Objective: Despite treatments which reduce relapses in multiple sclerosis (MS), many patients continue to experience progressive disability accumulation. MS is associated with metabolic disruptions and cerebral metabolic stress predisposes to...
4.
Jiang X, McGinley M, Johnston J, Alberts J, Bermel R, Ontaneda D, et al.
Mult Scler
. 2024 Dec;
31(1):81-92.
PMID: 39618060
Background: A digital adaptation of the nine-hole peg test (9HPT) was developed with the potential to provide novel disability features for patients with multiple sclerosis (PwMS). Objectives: The objectives were...
5.
Newsome S, Goldstick L, Robertson D, Bowen J, Naismith R, Townsend B, et al.
Ann Clin Transl Neurol
. 2024 Oct;
11(12):3215-3226.
PMID: 39460719
Objective: Subcutaneous ocrelizumab is being developed to provide treatment flexibility and additional choice to patients with multiple sclerosis. OCARINA I (NCT03972306) is an open-label, multicenter, Phase 1b, dose-finding study to...
6.
Hersh C, Sun Z, Conway D, Sotirchos E, Fitzgerald K, Hua L, et al.
Mult Scler Relat Disord
. 2024 Sep;
91:105847.
PMID: 39260226
Background: Two-stage models of heterogenous treatment effects (HTE) may advance personalized medicine in multiple sclerosis (MS). Brain atrophy is a relatively objective outcome measure that has strong relationships to MS...
7.
Ghezzi L, Tosti V, Shi L, Cantoni C, Mikesell R, Lancia S, et al.
J Neurol Neurosurg Psychiatry
. 2024 Aug;
96(2):158-169.
PMID: 39137977
Background: Calorie restriction (CR) ameliorates preclinical models of multiple sclerosis (MS) via multiple mechanisms. These include decreased leptin, a proinflammatory adipokine, but mechanistic studies in humans are lacking. Tests of...
8.
Brier M, Schindler S, Salter A, Perantie D, Shelley N, Judge B, et al.
Ann Neurol
. 2024 Jul;
96(3):453-459.
PMID: 38963256
The life expectancy of people with multiple sclerosis (MS) has increased, yet we have noted that development of a typical Alzheimer disease dementia syndrome is uncommon. We hypothesized that Alzheimer...
9.
Simpson A, Hu C, Mowry E, Naismith R, Fitzgerald K, Nourbakhsh B
Mult Scler
. 2024 Mar;
30(6):738-746.
PMID: 38525561
Background: Results of research on radiological hallmarks of multiple sclerosis (MS) fatigue have been conflicting. Objective: To investigate the associations of lesion and brain compartment volumes with fatigue severity and...
10.
Wooliscroft L, Salter A, Adusumilli G, Levasseur V, Sun P, Lancia S, et al.
Mult Scler Relat Disord
. 2024 Feb;
84:105494.
PMID: 38359694
Background And Objectives: Diffusion basis spectrum imaging (DBSI) extracts multiple anisotropic and isotropic diffusion tensors, providing greater histopathologic specificity than diffusion tensor imaging (DTI). Persistent black holes (PBH) represent areas...