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Robert S Fujinami

Explore the profile of Robert S Fujinami including associated specialties, affiliations and a list of published articles. Areas
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Articles 107
Citations 3094
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Recent Articles
1.
Libbey J, Fujinami R
Heliyon . 2023 Jul; 9(7):e18095. PMID: 37483821
Over the course of human history, numerous diseases have been caused by the transmission of viruses from an animal reservoir into the human population. The viruses of the genus are...
2.
Thompson J, Hu R, Huffaker T, Ramstead A, Ekiz H, Bauer K, et al.
J Immunol . 2023 Mar; 210(7):926-934. PMID: 36883849
The proinflammatory microRNA-155 (miR-155) is highly expressed in the serum and CNS lesions of patients with multiple sclerosis (MS). Global knockout (KO) of miR-155 in mice confers resistance to a...
3.
Sun Z, Zhao H, Fang D, Davis C, Shi D, Lei K, et al.
Neuron . 2022 Aug; 110(19):3106-3120.e7. PMID: 35961320
Breakdown of the blood-central nervous system barrier (BCNSB) is a hallmark of many neuroinflammatory disorders, such as multiple sclerosis (MS). Using a mouse model of MS, experimental autoimmune encephalomyelitis (EAE),...
4.
Sanchez J, DePaula-Silva A, Doty D, Hanak T, Truong A, Libbey J, et al.
Front Immunol . 2021 Sep; 12:621090. PMID: 34566948
Viral encephalitis is a major cause of morbidity and mortality, but the manifestation of disease varies greatly between individuals even in response to the same virus. Microglia are professional antigen...
5.
Sanchez J, Doty D, DePaula-Silva A, Brown D, Bell R, Klag K, et al.
J Neuroinflammation . 2020 Oct; 17(1):291. PMID: 33023618
Background: Multiple sclerosis (MS) is an inflammatory demyelinating disease that affects 2.5 million people worldwide. Growing evidence suggests that perturbation of the gut microbiota, the dense collection of microorganisms that...
6.
Libbey J, Fujinami R
Clin Microbiol Newsl . 2020 Apr; 24(10):73-76. PMID: 32287669
Viruses have been implicated in the initiation, progression, and exacerbation of several human autoimmune diseases, including multiple sclerosis. However, no single virus has been demonstrated as the etiologic agent. Multiple...
7.
Sanchez J, DePaula-Silva A, Libbey J, Fujinami R
Clin Immunol . 2020 Mar; 235:108379. PMID: 32156562
No abstract available.
8.
Patel D, Wallis G, Fujinami R, Wilcox K, Smith M
Epilepsia Open . 2019 Aug; 4(3):431-442. PMID: 31440724
Objective: C57BL/6J mice infected with Theiler's murine encephalomyelitis virus (TMEV) develop acute behavioral seizures in the first week of infection and later develop chronic epilepsy. The TMEV model provides a...
9.
DePaula-Silva A, Gorbea C, Doty D, Libbey J, Sanchez J, Hanak T, et al.
J Neuroinflammation . 2019 Jul; 16(1):152. PMID: 31325960
Background: In the healthy central nervous system (CNS), microglia are found in a homeostatic state and peripheral macrophages are absent from the brain. Microglia play key roles in maintaining CNS...
10.
Brown D, Soto R, Yandamuri S, Stone C, Dickey L, Gomes-Neto J, et al.
Elife . 2019 Jul; 8. PMID: 31309928
Symbiotic microbes impact the function and development of the central nervous system (CNS); however, little is known about the contribution of the microbiota during viral-induced neurologic damage. We identify that...