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Robert Ryall

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Articles 14
Citations 559
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Recent Articles
1.
Nemes E, Geldenhuys H, Rozot V, Rutkowski K, Ratangee F, Bilek N, et al.
N Engl J Med . 2018 Jul; 379(2):138-149. PMID: 29996082
Background: Recent Mycobacterium tuberculosis infection confers a predisposition to the development of tuberculosis disease, the leading killer among global infectious diseases. H4:IC31, a candidate subunit vaccine, has shown protection against...
2.
Geldenhuys H, Mearns H, Miles D, Tameris M, Hokey D, Shi Z, et al.
Vaccine . 2015 Jun; 33(30):3592-9. PMID: 26048780
Background: New, more effective vaccines to prevent tuberculosis (TB) disease are needed urgently. H4:IC31 is an investigational vaccine that contains a fusion protein of the immunodominant antigens TB10.4 and Ag85B,...
3.
Bernard M, Barban V, Pradezynski F, De Montfort A, Ryall R, Caillet C, et al.
PLoS One . 2015 Apr; 10(4):e0121518. PMID: 25837802
HSV-2 vaccine is needed to prevent genital disease, latent infection, and virus transmission. A replication-deficient mutant virus (dl5-29) has demonstrated promising efficacy in animal models of genital herpes. However, the...
4.
Lagos R, Papa T, Munoz A, Ryall R, Pina M, Bassily E
Hum Vaccin . 2006 Oct; 1(6):228-31. PMID: 17012878
Immune responses to meningococcal conjugate (Menactra; MCV-4) and plain polysaccharide (Menomune-A/C/Y/W-135; PSV-4) vaccines against serogroups A, C, Y, and W-135 were assessed in 220 of 1037 Chilean children aged 2...
5.
Keyserling H, Papa T, Koranyi K, Ryall R, Bassily E, Bybel M, et al.
Arch Pediatr Adolesc Med . 2005 Oct; 159(10):907-13. PMID: 16203934
Objective: A meningococcal (groups A, C, Y, and W-135) polysaccharide diphtheria toxoid conjugate vaccine (MCV-4; Menactra; Sanofi Pasteur Inc, Swiftwater, Pa) was developed to improve the profile of currently licensed...
6.
Pichichero M, Casey J, Blatter M, Rothstein E, Ryall R, Bybel M, et al.
Pediatr Infect Dis J . 2005 Jan; 24(1):57-62. PMID: 15665711
Background: A quadrivalent meningococcal diphtheria conjugate vaccine (MCV-4) has been developed to provide T-cell dependent immune responses against 4 major disease-causing serogroups (A, C, Y, W-135). Methods: In a comparative,...
7.
Cai X, Lei Q, Lamb D, Shannon A, Jacoby J, Kruk J, et al.
Anal Chem . 2004 Dec; 76(24):7387-90. PMID: 15595884
Hydrogen peroxide has been used to cleave the native Neisseria meningiditis polysaccharide (PS) from mega-Dalton molecular weight to a smaller size (approximately 20 kDa) depolymerized polysaccharide. The polysaccharide was examined...
8.
Lei Q, Lamb D, Shannon A, Cai X, Heller R, Huang M, et al.
J Chromatogr B Analyt Technol Biomed Life Sci . 2004 Nov; 813(1-2):103-12. PMID: 15556522
An LC-MS/MS method for determination of the break down product of N-ethyl-N'-(3-dimethylaminopropyl) carbodiimide (EDC) urea derivative, EDU, has been developed and validated for monitoring the residual coupling reagents. Results indicate...
9.
Rennels M, King Jr J, Ryall R, Papa T, Froeschle J
Pediatr Infect Dis J . 2004 May; 23(5):429-35. PMID: 15131466
Background: Young children have the highest incidence of meningococcal infection. Approximately 50% of disease in United States children less than 2 years of age is caused by serogroups C and...
10.
Joseph H, Balmer P, Bybel M, Papa T, Ryall R, Borrow R
Clin Diagn Lab Immunol . 2004 Jan; 11(1):1-5. PMID: 14715537
Meningococcal serogroup-specific immunoglobulin G (IgG), IgG1, and IgG2 concentrations were assigned to three reference sera, CDC 1992, 89-SF, and 96/562, for meningococcal serogroups A, C, Y, and W135 via the...