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Robert R Gilmont

Explore the profile of Robert R Gilmont including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 340
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Recent Articles
1.
Benndorf R, Gilmont R, Hirano S, Ransom R, Jungblut P, Bommer M, et al.
Cell Stress Chaperones . 2018 Mar; 23(5):813-826. PMID: 29542021
When analyzing small stress proteins of rat and human tissues by electrophoretic methods followed by western blotting, and using the anti-HspB1/anti-HspB5 antibody clone 8A7, we unexpectedly found a protein with...
2.
Raghavan S, Miyasaka E, Gilmont R, Somara S, Teitelbaum D, Bitar K
Surgery . 2014 Mar; 155(4):668-74. PMID: 24582493
Background: The internal anal sphincter (IAS) is a major contributing factor to pressure within the anal canal and is required for maintenance of rectoanal continence. IAS damage or weakening results...
3.
Gilmont R, Raghavan S, Somara S, Bitar K
Tissue Eng Part A . 2013 Dec; 20(11-12):1603-11. PMID: 24328537
Muscle replacement for patients suffering from extensive tissue loss or dysfunction is a major objective of regenerative medicine. To achieve functional status, bioengineered muscle replacement constructs require innervation. Here we...
4.
Raghavan S, Gilmont R, Bitar K
Biomaterials . 2013 Jun; 34(28):6649-58. PMID: 23746858
Enteric neuronal progenitor cells are neural crest-derived stem cells that can be isolated from fetal, post-natal and adult gut. Neural stem cell transplantation is an emerging therapeutic paradigm to replace...
5.
Zakhem E, Raghavan S, Gilmont R, Bitar K
Biomaterials . 2012 Apr; 33(19):4810-7. PMID: 22483012
Intestinal tissue engineering is an emerging field due to a growing demand for intestinal lengthening and replacement procedures secondary to massive resections of the bowel. Here, we demonstrate the potential...
6.
Raghavan S, Gilmont R, Miyasaka E, Somara S, Srinivasan S, Teitelbaum D, et al.
Gastroenterology . 2011 Apr; 141(1):310-9. PMID: 21463628
Background & Aims: To restore fecal continence, the weakened pressure of the internal anal sphincter (IAS) must be increased. We bioengineered intrinsically innervated human IAS to emulate sphincteric physiology in...
7.
Somara S, Bashllari D, Gilmont R, Bitar K
Am J Physiol Gastrointest Liver Physiol . 2011 Mar; 300(6):G1022-32. PMID: 21372166
Caveolin-1 (cav-1) plays a key role in PKC-α and RhoA signaling pathways during acetylcholine (ACh)-induced contraction of colonic smooth muscle cells (CSMC). Aged rat CSMC showed sluggish contractility, concomitant with...
8.
Miyasaka E, Raghavan S, Gilmont R, Mittal K, Somara S, Bitar K, et al.
Pediatr Surg Int . 2010 Nov; 27(2):137-43. PMID: 21046117
Purpose: Our laboratory has developed and implanted a novel bioengineered internal anal sphincter (IAS) to treat anal incontinence. Fibroblast growth factor-2 (FGF-2) has been used in mice; however, the optimal...
9.
Somara S, Gilmont R, Varadarajan S, Bitar K
Am J Physiol Gastrointest Liver Physiol . 2010 Sep; 299(5):G1164-76. PMID: 20829522
Small heat shock proteins HSP27 and HSP20 have been implicated in regulation of contraction and relaxation in smooth muscle. Activation of PKC-α promotes contraction by phosphorylation of HSP27 whereas activation...
10.
Raghavan S, Miyasaka E, Hashish M, Somara S, Gilmont R, Teitelbaum D, et al.
Am J Physiol Gastrointest Liver Physiol . 2010 Jun; 299(2):G430-9. PMID: 20558766
We have previously developed bioengineered three-dimensional internal anal sphincter (IAS) rings from circular smooth muscle cells isolated from rabbit and human IAS. We provide proof of concept that bioengineered mouse...