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Robert Plenge

Explore the profile of Robert Plenge including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 1993
Followers 0
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Recent Articles
1.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature . 2023 Feb; 615(7952):E19. PMID: 36829046
No abstract available.
2.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature . 2023 Jan; 613(7944):508-518. PMID: 36653562
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%)....
3.
Yousri N, Bayoumy K, Elhaq W, Mohney R, Al Emadi S, Hammoudeh M, et al.
Sci Rep . 2017 Aug; 7(1):9137. PMID: 28831053
Recent metabolomics studies of Rheumatoid Arthritis (RA) reported few metabolites that were associated with the disease, either due to small cohort sizes or limited coverage of metabolic pathways. Our objective...
4.
Sieberts S, Zhu F, Garcia-Garcia J, Stahl E, Pratap A, Pandey G, et al.
Nat Commun . 2016 Oct; 7:13205. PMID: 27721464
No abstract available.
5.
Sieberts S, Zhu F, Garcia-Garcia J, Stahl E, Pratap A, Pandey G, et al.
Nat Commun . 2016 Aug; 7:12460. PMID: 27549343
Rheumatoid arthritis (RA) affects millions world-wide. While anti-TNF treatment is widely used to reduce disease progression, treatment fails in ∼one-third of patients. No biomarker currently exists that identifies non-responders before...
6.
Yarwood A, Viatte S, Okada Y, Plenge R, Yamamoto K, Barton A, et al.
Ann Rheum Dis . 2015 Sep; 75(1):317-20. PMID: 26386125
Objectives: A recent study identified 16 genetic variants associated with N-glycosylation of human IgG. Several of the genomic regions where these single nucleotide polymorphisms (SNPs) reside have also been associated...
7.
Uchiyama E, Faez S, Nasir H, Unizony S, Plenge R, Papaliodis G, et al.
Ophthalmic Epidemiol . 2015 Mar; 22(2):139-41. PMID: 25777314
Purpose: To report on the accuracy of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for identifying patients with polymyalgia rheumatica (PMR) and concurrent noninfectious inflammatory ocular...
8.
Bao Y, Curhan G, Merriman T, Plenge R, Kraft P, Choi H
Ann Rheum Dis . 2015 Feb; 74(7):1394-8. PMID: 25667207
Background: Diuretic-induced gout might occur only among those with a genetic predisposition to hyperuricaemia, as suggested by a recent study with 108 self-reported gout cases. Methods: We examined the role...
9.
Chhibber A, Kroetz D, Tantisira K, McGeachie M, Cheng C, Plenge R, et al.
Pharmacogenomics . 2014 Dec; 15(16):2025-48. PMID: 25521360
The pharmacokinetic and pharmacodynamic disciplines address pharmacological traits, including efficacy and adverse events. Pharmacogenomics studies have identified pervasive genetic effects on treatment outcomes, resulting in the development of genetic biomarkers...
10.
Sinnott J, Dai W, Liao K, Shaw S, Ananthakrishnan A, Gainer V, et al.
Hum Genet . 2014 Jul; 133(11):1369-82. PMID: 25062868
To reduce costs and improve clinical relevance of genetic studies, there has been increasing interest in performing such studies in hospital-based cohorts by linking phenotypes extracted from electronic medical records...