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Robert P Clayton

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Articles 16
Citations 206
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Recent Articles
1.
Guillory A, Clayton R, Prasai A, Jay J, Wetzel M, El Ayadi A, et al.
J Surg Res . 2018 Nov; 232:154-159. PMID: 30463712
Background: It has been previously shown that anesthesia and analgesia can affect outcomes in the rat burn model and that buprenorphine alleviated pain without drastically altering the outcomes of interest....
2.
Clayton R, Herndon D, Abate N, Porter C
J Burn Care Res . 2018 Jun; 39(5):713-723. PMID: 29931151
Severe burns represent a unique form of trauma in terms of the magnitude and persistence of the stress response they incur. Given advances in acute burn care in the last...
3.
Hundeshagen G, Herndon D, Clayton R, Wurzer P, McQuitty A, Jennings K, et al.
Lancet Child Adolesc Health . 2018 Mar; 1(4):293-301. PMID: 29581998
Background: Sepsis, trauma, and burn injury acutely depress systolic and diastolic cardiac function; data on long-term cardiac sequelae of pediatric critical illness are sparse. This study evaluated long-term systolic and...
4.
Guillory A, Clayton R, Prasai A, El Ayadi A, Herndon D, Finnerty C
PLoS One . 2017 Dec; 12(12):e0189527. PMID: 29232706
Burn injury detrimentally affects the myocardium, primarily due to over-activation of β-adrenergic receptors (β-AR). Autopsy reports from our institution reveal that patients often suffer from right ventricle (RV) failure. Since...
5.
Foncerrada G, Lima F, Clayton R, Mlcak R, Enkhbaatar P, Herndon D, et al.
J Burn Care Res . 2017 Jun; 38(6):396-402. PMID: 28570317
This pilot study was conducted to profile safety of nebulized racemic epinephrine when used as a therapy for smoke inhalation injury in severely burned children. We enrolled 16 patients who...
6.
Wurzer P, Cole M, Clayton R, Hundeshagen G, Nunez Lopez O, Cambiaso-Daniel J, et al.
Burns . 2017 Apr; 43(5):987-992. PMID: 28420570
Objective: Burn-related immunosuppression can promote human herpesviridae infections. However, the effect of these infections on morbidity and mortality after pediatric burn injuries is unclear. Methods: We retrospectively analyzed pediatric patients...
7.
Clayton R, Wurzer P, Andersen C, Mlcak R, Herndon D, Suman O
Burns . 2016 Dec; 43(4):796-803. PMID: 27908464
Introduction: Burns lead to persistent and detrimental muscle breakdown and weakness. Standard treatment at our institution includes a voluntary 12-week rehabilitative exercise program to limit and reverse the effects of...
8.
Wurzer P, Guillory A, Parvizi D, Clayton R, Branski L, Kamolz L, et al.
Burns . 2016 Aug; 43(1):25-33. PMID: 27515422
Objective: The contribution of human herpes viruses, including herpes simplex virus (HSV), cytomegalovirus (CMV), and varicella zoster virus (VZV) to morbidity and mortality after burns remains controversial. This systematic review...
9.
Wurzer P, Branski L, Clayton R, Hundeshagen G, Forbes A, Voigt C, et al.
Shock . 2016 Jul; 46(5):486-491. PMID: 27380530
Purpose: The aim of this study was to quantify the effect of propranolol on hemodynamic parameters assessed using the PiCCO system in burned children. Methods: We analyzed hemodynamic data from...
10.
Wurzer P, Voigt C, Clayton R, Andersen C, Mlcak R, Kamolz L, et al.
Surgery . 2016 Jun; 160(3):781-8. PMID: 27267551
Background: We have reported that a 12-week exercise program is beneficial for the exercise performance of severely burned children. It is not known, however, whether the beneficial effects remain at...