Robert Orlando
Overview
Explore the profile of Robert Orlando including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
144
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Recent Articles
1.
Shahid A, Chen M, Yeung S, Parsa C, Orlando R, Huang Y
Front Pharmacol
. 2023 Sep;
14:1244150.
PMID: 37745066
(GL) commonly known as "Lingzhi", is a well-known medicinal mushroom with antioxidant and anti-cancer activity. This study examined the effects of a commercial GL product (GLSF) containing the spore and...
2.
Shamim M, Shahid A, Sardar P, Yeung S, Reyes J, Kim J, et al.
Nanomaterials (Basel)
. 2023 Mar;
13(5).
PMID: 36903807
The R-carvedilol enantiomer, present in the racemic mixture of the chiral drug carvedilol, does not bind to the β-adrenergic receptors, but exhibits skin cancer preventive activity. For skin delivery, R-carvedilol-loaded...
3.
Lambros M, Moreno J, Fei Q, Parsa C, Orlando R, Van Haute L
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36902486
Oral mucositis is a common side effect of cancer treatment, and in particular of treatment with the mTORC1 inhibitor everolimus. Current treatment methods are not efficient enough and a better...
4.
Shahid A, Chen M, Lin C, Andresen B, Parsa C, Orlando R, et al.
Cancers (Basel)
. 2023 Feb;
15(3).
PMID: 36765542
The current study evaluated the effects of the β-blocker carvedilol on benzo(a)pyrene (B(a)P) and its active metabolite benzo(a)pyrene diol epoxide (BPDE)-induced lung toxicity, inflammation and carcinogenesis and explored the potential...
5.
Liu M, Liu T, Yeung S, Wang Z, Andresen B, Parsa C, et al.
Precis Clin Med
. 2022 Jun;
4(4):231-245.
PMID: 35692861
The medicinal mushroom (GL, Reishi or Lingzhi) exhibits an inhibitory effect on cancers. However, the underlying mechanism of the antitumor activity of GL is not fully understood. In this study,...
6.
Shahid A, Huang M, Liu M, Shamim M, Parsa C, Orlando R, et al.
PLoS One
. 2022 Mar;
17(3):e0265615.
PMID: 35312729
The medicinal mushroom Ganoderma lucidum is traditionally used for treating multiple diseases, including cancer. This study examined skin cancer preventive activity of a commercial product containing spore and fruiting body...
7.
Shamim M, Yeung S, Shahid A, Chen M, Wang J, Desai P, et al.
Int J Pharm
. 2021 Nov;
611:121302.
PMID: 34793935
The β-blocker carvedilol prevents ultraviolet (UV)-induced skin cancer, but systemic drug administration may cause unwanted cadiovascular effects. To overcome this limitation, a topical delivery system based on transfersome (T-CAR) was...
8.
Liang S, Shamim M, Shahid A, Chen M, Cleveland K, Parsa C, et al.
Cancer Prev Res (Phila)
. 2021 Mar;
14(5):527-540.
PMID: 33648941
Skin cancer is the most common malignancy worldwide and is rapidly rising in incidence, representing a significant public health challenge. The β-blocker, carvedilol, has shown promising effects in preventing skin...
9.
Parsa C, Orlando R, Marcus M, Guo J, Rupani R
J Surg Case Rep
. 2019 Dec;
2019(9):rjz245.
PMID: 31807268
Malignancies characterized histologically by high-grade monotonous small round blue cells (SRBCs) belong to a heterogeneous group of neoplasms often referred to as Ewing family of tumors. The most common molecular...
10.
Huang K, Liang S, Yeung S, Oiyemhonlan E, Cleveland K, Parsa C, et al.
Cancer Prev Res (Phila)
. 2017 Sep;
10(10):598-606.
PMID: 28912118
In previous studies, the β-blocker carvedilol inhibited EGF-induced epidermal cell transformation and chemical carcinogen-induced mouse skin hyperplasia. As exposure to ultraviolet (UV) radiation leads to skin cancer, the present study...