Robert M Bradley
Overview
Explore the profile of Robert M Bradley including associated specialties, affiliations and a list of published articles.
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28
Citations
310
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Recent Articles
1.
Sung H, Vesela I, Driks H, Ferrario C, Mistretta C, Bradley R, et al.
Curr Biol
. 2022 Aug;
32(19):4103-4113.e4.
PMID: 35977546
Elevated sugar consumption is associated with an increased risk for metabolic diseases. Whereas evidence from humans, rodents, and insects suggests that dietary sucrose modifies sweet taste sensation, understanding of peripheral...
2.
Donnelly C, Kumari A, Li L, Vesela I, Bradley R, Mistretta C, et al.
Cell Tissue Res
. 2022 Jun;
389(2):371.
PMID: 35697944
No abstract available.
3.
Donnelly C, Kumari A, Li L, Vesela I, Bradley R, Mistretta C, et al.
Cell Tissue Res
. 2021 Dec;
387(2):225-247.
PMID: 34859291
The fungiform papilla (FP) is a gustatory and somatosensory structure incorporating chorda tympani (CT) nerve fibers that innervate taste buds (TB) and also contain somatosensory endings for touch and temperature....
4.
Mistretta C, Bradley R
Curr Opin Physiol
. 2021 Mar;
20:165-173.
PMID: 33681545
When solid or liquid stimuli contact the tongue tip during eating, the sensations of taste, touch and temperature are immediately evoked, and tongue function relies on these simultaneous multimodal responses....
5.
Tang T, Donnelly C, Shah A, Bradley R, Mistretta C, Pierchala B
Sci Rep
. 2020 Dec;
10(1):22117.
PMID: 33335119
During development of the peripheral taste system, oral sensory neurons of the geniculate ganglion project via the chorda tympani nerve to innervate taste buds in fungiform papillae. Germline deletion of...
6.
Donnelly C, Shah A, Mistretta C, Bradley R, Pierchala B
Proc Natl Acad Sci U S A
. 2017 Dec;
115(3):E516-E525.
PMID: 29282324
The development of the taste system relies on the coordinated regulation of cues that direct the simultaneous development of both peripheral taste organs and innervating sensory ganglia, but the underlying...
7.
Kumari A, Ermilov A, Grachtchouk M, Dlugosz A, Allen B, Bradley R, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(48):E10369-E10378.
PMID: 29133390
Striking taste disturbances are reported in cancer patients treated with Hedgehog (HH)-pathway inhibitor drugs, including sonidegib (LDE225), which block the HH pathway effector Smoothened (SMO). We tested the potential for...
8.
Yokota Y, Bradley R
Neuroscience
. 2017 Nov;
367:147-158.
PMID: 29097269
Afferent chorda tympani (CT) fibers innervating anterior tongue fungiform papillae have neuron cell bodies in the geniculate ganglion (GG). To characterize electrophysiological and receptive field properties, we recorded extracellular responses...
9.
Yokota Y, Bradley R
J Neurophysiol
. 2016 Apr;
115(6):3062-72.
PMID: 27030734
Afferent chorda tympani (CT) fibers innervating taste and somatosensory receptors in fungiform papillae have neuron cell bodies in the geniculate ganglion (GG). The GG/CT fibers branch in the tongue to...
10.
Kumari A, Ermilov A, Allen B, Bradley R, Dlugosz A, Mistretta C
J Neurophysiol
. 2014 Nov;
113(3):1034-40.
PMID: 25392175
Taste sensation on the anterior tongue requires chorda tympani nerve function and connections with continuously renewing taste receptor cells. However, it is unclear which signaling pathways regulate the receptor cells...