Robert L Judson
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Explore the profile of Robert L Judson including associated specialties, affiliations and a list of published articles.
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15
Citations
1500
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Recent Articles
1.
Botton T, Talevich E, Mishra V, Zhang T, Shain A, Berquet C, et al.
Cell Rep
. 2019 Oct;
29(3):573-588.e7.
PMID: 31618628
BRAF fusions are detected in numerous neoplasms, but their clinical management remains unresolved. We identified six melanoma lines harboring BRAF fusions representative of the clinical cases reported in the literature....
2.
Zhang Y, Judson R
Cytometry A
. 2018 Oct;
93(11):1125-1131.
PMID: 30343513
Digital holographic cytometry (DHC) and other methods of quantitative phase imaging permit extended time-lapse imaging of mammalian cells in the absence of induced cellular toxicity. Manufactured DHC platforms equipped with...
3.
Zeng H, Jorapur A, Shain A, Lang U, Torres R, Zhang Y, et al.
Cancer Cell
. 2018 Jul;
34(1):56-68.e9.
PMID: 29990501
Loss of the CDKN2A tumor suppressor is associated with melanoma metastasis, but the mechanisms connecting the phenomena are unknown. Using CRISPR-Cas9 to engineer a cellular model of melanoma initiation from...
4.
Yeh I, Lang U, Durieux E, Tee M, Jorapur A, Shain A, et al.
Nat Commun
. 2017 Sep;
8(1):644.
PMID: 28935960
Deep penetrating nevus (DPN) is characterized by enlarged, pigmented melanocytes that extend through the dermis. DPN can be difficult to distinguish from melanoma but rarely displays aggressive biological behavior. Here,...
5.
Hejna M, Jorapur A, Song J, Judson R
Sci Rep
. 2017 Sep;
7(1):11943.
PMID: 28931937
Digital holographic cytometry (DHC) permits label-free visualization of adherent cells. Dozens of cellular features can be derived from segmentation of hologram-derived images. However, the accuracy of single cell classification by...
6.
Huskey N, Guo T, Evason K, Momcilovic O, Pardo D, Creasman K, et al.
Stem Cell Reports
. 2015 Mar;
4(3):374-89.
PMID: 25733019
Embryonic stem cells (ESCs) have adopted an accelerated cell-cycle program with shortened gap phases and precocious expression of cell-cycle regulatory proteins, including cyclins and cyclin-dependent kinases (CDKs). We examined the...
7.
Parchem R, Ye J, Judson R, LaRussa M, Krishnakumar R, Blelloch A, et al.
Cell Stem Cell
. 2014 Mar;
14(5):617-31.
PMID: 24630794
Ectopic expression of specific factors such as Oct4, Sox2, and Klf4 (OSK) is sufficient to reprogram somatic cells into induced pluripotent stem cells (iPSCs). In this study, we examine the...
8.
Judson R, Greve T, Parchem R, Blelloch R
Nat Struct Mol Biol
. 2013 Sep;
20(10):1227-35.
PMID: 24037508
Individual microRNAs (miRNAs) can target hundreds of mRNAs forming networks of presumably cooperating genes. To test this presumption, we functionally screened miRNAs and their targets in the context of dedifferentiation...
9.
Greve T, Judson R, Blelloch R
Annu Rev Cell Dev Biol
. 2013 Jul;
29:213-239.
PMID: 23875649
In the past decade, significant progress has been made in understanding both microRNA function and cellular pluripotency. Here we review the intersection of these two exciting fields. While microRNAs are...
10.
Subramanyam D, Lamouille S, Judson R, Liu J, Bucay N, Derynck R, et al.
Nat Biotechnol
. 2011 Apr;
29(5):443-8.
PMID: 21490602
The embryonic stem cell-specific cell cycle-regulating (ESCC) family of microRNAs (miRNAs) enhances reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells. Here we show that the human ESCC miRNA...