Robert L Furler OBrien
Overview
Explore the profile of Robert L Furler OBrien including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
53
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0
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Recent Articles
1.
Martinez-Meza S, Premeaux T, Cirigliano S, Friday C, Michael S, Mediouni S, et al.
J Neuroinflammation
. 2025 Mar;
22(1):66.
PMID: 40045391
Background: HIV-1-associated neurocognitive impairment (HIV-1-NCI) is marked by ongoing and chronic neuroinflammation with loss and decline in neuronal function even when antiretroviral drug therapy (ART) successfully suppresses viral replication. Microglia,...
2.
Prigann J, Tavora R, Furler OBrien R, Schulze-Gahmen U, Boehm D, Roan N, et al.
Nat Microbiol
. 2024 Sep;
9(10):2470-2472.
PMID: 39289508
No abstract available.
3.
Crater J, Dunn D, Nixon D, Furler OBrien R
bioRxiv
. 2024 Feb;
PMID: 38405733
During cell movement, cortical actin balances mechanical and osmotic forces to maintain cell function while providing the scaffold for cell shape. Migrating CD4 T cells have a polarized structure with...
4.
Yang L, Kim T, Han Y, Nair M, Harschnitz O, Zhu J, et al.
Cell Stem Cell
. 2024 Jan;
31(2):196-211.e6.
PMID: 38237586
COVID-19 patients commonly present with signs of central nervous system and/or peripheral nervous system dysfunction. Here, we show that midbrain dopamine (DA) neurons derived from human pluripotent stem cells (hPSCs)...
5.
Lyons D, Kumar P, Roan N, Defechereux P, Feschotte C, Lange U, et al.
Viruses
. 2023 Nov;
15(11).
PMID: 38005849
Despite remarkable progress, a cure for HIV-1 infection remains elusive. Rebound competent latent and transcriptionally active reservoir cells persevere despite antiretroviral therapy and rekindle infection due to inefficient proviral silencing....
6.
Crater J, Dunn D, Nixon D, Furler OBrien R
Biomedicines
. 2023 Oct;
11(10).
PMID: 37892982
CD4 T cells have orchestrated and regulated immunity since the introduction of jawed vertebrates, yet our understanding of CD4 T cell evolution, development, and cellular physiology has only begun to...
7.
Ikegame S, Carmichael J, Wells H, Furler OBrien R, Acklin J, Chiu H, et al.
Nat Microbiol
. 2023 May;
8(6):1108-1122.
PMID: 37142773
Morbilliviruses are among the most contagious viral pathogens of mammals. Although previous metagenomic surveys have identified morbillivirus sequences in bats, full-length morbilliviruses from bats are limited. Here we characterize the...
8.
Crater J, Nixon D, Furler OBrien R
Front Cell Infect Microbiol
. 2022 Dec;
12:1068436.
PMID: 36467738
Human Immunodeficiency virus type 1 (HIV-1) relies on host cell metabolism for all aspects of viral replication. Efficient HIV-1 entry, reverse transcription, and integration occurs in activated T cells because...