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Robert Krautz

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Articles 18
Citations 250
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Recent Articles
1.
van den Ameele J, Trauner M, Hormanseder E, Donovan A, Llora-Batlle O, Cheetham S, et al.
PLoS Biol . 2025 Mar; 23(3):e3002944. PMID: 40067796
Histone modifications play a key role in regulating gene expression and cell fate during development and disease. Current methods for cell-type-specific genome-wide profiling of histone modifications require dissociation and isolation...
2.
Schmidt Kjolner Hansen S, Krautz R, Rago D, Havelund J, Stigliani A, Faergeman N, et al.
Nat Commun . 2024 Jun; 15(1):4711. PMID: 38830841
The fetal development of organs and functions is vulnerable to perturbation by maternal inflammation which may increase susceptibility to disorders after birth. Because it is not well understood how the...
3.
Wenger A, Biran A, Alcaraz N, Redo-Riveiro A, Sell A, Krautz R, et al.
Nat Genet . 2023 Sep; 55(9):1567-1578. PMID: 37666988
Modified parental histones are segregated symmetrically to daughter DNA strands during replication and can be inherited through mitosis. How this may sustain the epigenome and cell identity remains unknown. Here...
4.
van Duin L, Krautz R, Rennie S, Andersson R
Mol Syst Biol . 2023 May; 19(7):e11392. PMID: 37158788
Many genes are co-expressed and form genomic domains of coordinated gene activity. However, the regulatory determinants of domain co-activity remain unclear. Here, we leverage human individual variation in gene expression...
5.
Tang J, Krautz R, Llora-Batlle O, Hakes A, Fox P, Brand A
STAR Protoc . 2022 Nov; 3(4):101788. PMID: 36345375
NanoDam is a technique for genome-wide profiling of the binding targets of any endogenously tagged chromatin-binding protein , without the need for antibodies, crosslinking, or immunoprecipitation. Here, we explain the...
6.
Tang J, Hakes A, Krautz R, Suzuki T, Contreras E, Fox P, et al.
Dev Cell . 2022 Apr; 57(9):1193-1207.e7. PMID: 35483359
Temporal patterning of neural progenitors is an evolutionarily conserved strategy for generating neuronal diversity. Type II neural stem cells in the Drosophila central brain produce transit-amplifying intermediate neural progenitors (INPs)...
7.
van den Ameele J, Krautz R, Cheetham S, Donovan A, Llora-Batlle O, Yakob R, et al.
Nat Commun . 2022 Apr; 13(1):2210. PMID: 35468895
The Notch signalling pathway is a master regulator of cell fate transitions in development and disease. In the brain, Notch promotes neural stem cell (NSC) proliferation, regulates neuronal migration and...
8.
Bakoulis S, Krautz R, Alcaraz N, Salvatore M, Andersson R
Nucleic Acids Res . 2022 Feb; 50(4):2111-2127. PMID: 35166831
Transposable elements are an abundant source of transcription factor binding sites, and favorable genomic integration may lead to their recruitment by the host genome for gene regulatory functions. However, it...
9.
Krautz R, Khalili D, Theopold U
Elife . 2020 Dec; 9. PMID: 33377870
Postmitotic tissues are incapable of replacing damaged cells through proliferation, but need to rely on buffering mechanisms to prevent tissue disintegration. By constitutively activating the Ras/MAPK-pathway via -overexpression in the...
10.
Dziedziech A, Schmid M, Arefin B, Kienzle T, Krautz R, Theopold U
Data Brief . 2019 Aug; 25:104229. PMID: 31367663
Insect hemolymph coagulation: Kinetics of classically and non-classically secreted clotting factors Schmid et al., 2019. The linked article demonstrates the localization of two secretory proteins in , Prophenoloxidase (PPO2) and ...