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Robert J J Jansens

Explore the profile of Robert J J Jansens including associated specialties, affiliations and a list of published articles. Areas
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Citations 113
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Recent Articles
1.
Verhamme R, Jansens R, Liu J, Van Raemdonck F, Van Waesberghe C, Nicholson L, et al.
J Virol . 2025 Jan; 99(2):e0201924. PMID: 39791911
Alpha-ketoglutarate-dependent dioxygenase, also known as fat mass and obesity-associated protein (FTO), is an RNA demethylase that mediates the demethylation of N,2-O-dimethyladenosine (m6Am) and N-methyladenosine (m6A). Both m6Am and m6A are...
2.
Hermans L, Denaeghel S, Jansens R, De Pelsmaeker S, Van Nieuwerburgh F, Deforce D, et al.
Front Immunol . 2023 Sep; 14:1219078. PMID: 37662951
Liver-resident NK (lrNK) cells have been studied in humans as well as in mice. Unfortunately, important differences have been observed between murine and human lrNK cells, complicating the extrapolation of...
3.
Jansens R, Olarerin-George A, Verhamme R, Mirza A, Jaffrey S, Favoreel H
iScience . 2023 Aug; 26(8):107310. PMID: 37575180
The mechanisms by which viruses regulate host mRNAs during infection are still poorly understood. Several host transcripts that encode proteins that contribute to the anti-viral response contain the N6-methyladenosine nucleotide...
4.
Delva J, Daled S, Van Waesberghe C, Almey R, Jansens R, Deforce D, et al.
J Virol . 2022 Dec; 96(24):e0115822. PMID: 36453884
Pseudorabies virus (PRV) is a member of the alphaherpesvirus subfamily and the causative agent of Aujeszky's disease in pigs. Driven by the large economic losses associated with PRV infection, several...
5.
Jansens R, Verhamme R, Mirza A, Olarerin-George A, Van Waesberghe C, Jaffrey S, et al.
Cell Rep . 2022 Jul; 40(3):111107. PMID: 35858564
Chemical modifications of mRNA, the so-called epitranscriptome, represent an additional layer of post-transcriptional regulation of gene expression. The most common epitranscriptomic modification, N6-methyladenosine (m6A), is generated by a multi-subunit methyltransferase...
6.
Vermeire B, Gonzalez L, Jansens R, Cox E, Devriendt B
Vet Res . 2021 Aug; 52(1):107. PMID: 34344443
No abstract available.
7.
Vermeire B, Gonzalez L, Jansens R, Cox E, Devriendt B
Vet Res . 2021 Jun; 52(1):94. PMID: 34174960
Small intestinal organoids, or enteroids, represent a valuable model to study host-pathogen interactions at the intestinal epithelial surface. Much research has been done on murine and human enteroids, however only...
8.
Jansens R, Marmiroli S, Favoreel H
Pathogens . 2020 Nov; 9(11). PMID: 33167340
The US3 serine/threonine protein kinase is conserved among the alphaherpesvirus family and represents an important virulence factor. US3 plays a role in viral nuclear egress, induces dramatic alterations of the...
9.
Jansens R, Tishchenko A, Favoreel H
J Virol . 2020 Feb; 94(8). PMID: 32024778
Tunneling nanotubes (TNTs) are actin-based intercellular conduits that connect distant cells and allow intercellular transfer of molecular information, including genetic information, proteins, lipids, and even organelles. Besides providing a means...
10.
Jansens R, Van Den Broeck W, De Pelsmaeker S, Lamote J, Van Waesberghe C, Couck L, et al.
J Virol . 2017 Jul; 91(19). PMID: 28747498
Tunneling nanotubes (TNTs) are long bridge-like structures that connect eukaryotic cells and mediate intercellular communication. We found earlier that the conserved alphaherpesvirus US3 protein kinase induces long cell projections that...