Robert J Bache
Overview
Explore the profile of Robert J Bache including associated specialties, affiliations and a list of published articles.
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59
Citations
1955
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Recent Articles
1.
Fassett J, Xu X, Kwak D, Zhu G, Fassett E, Zhang P, et al.
J Mol Cell Cardiol
. 2019 Mar;
130:49-58.
PMID: 30910669
Adenosine exerts numerous protective actions in the heart, including attenuation of cardiac hypertrophy. Adenosine kinase (ADK) converts adenosine to adenosine monophosphate (AMP) and is the major route of myocardial adenosine...
2.
3.
Wang H, Kwak D, Fassett J, Liu X, Yao W, Weng X, et al.
Basic Res Cardiol
. 2017 Mar;
112(3):25.
PMID: 28349258
Inflammatory responses play an important role in the development of left ventricular (LV) hypertrophy and dysfunction. Recent studies demonstrated that increased T-cell infiltration and T-cell activation contribute to LV hypertrophy...
4.
Zhang P, Fassett J, Zhu G, Li J, Hu X, Xu X, et al.
Vasc Med
. 2017 Feb;
22(3):179-188.
PMID: 28145161
Pharmacologic inhibition of nitric oxide production inhibits growth of coronary collateral vessels. Dimethylarginine dimethylaminohydrolase 1 (DDAH1) is the major enzyme that degrades asymmetric dimethylarginine (ADMA), a potent inhibitor of nitric...
5.
Wang H, Kwak D, Fassett J, Hou L, Xu X, Burbach B, et al.
Hypertension
. 2016 Jul;
68(3):688-96.
PMID: 27432861
The inflammatory response regulates congestive heart failure (CHF) development. T cell activation plays an important role in tissue inflammation. We postulate that CD28 or B7 deficiency inhibits T cell activation...
6.
Wang H, Hou L, Kwak D, Fassett J, Xu X, Chen A, et al.
Hypertension
. 2016 May;
68(1):114-22.
PMID: 27160197
Congestive heart failure (CHF) is associated with an increase of leukocyte infiltration, proinflammatory cytokines, and fibrosis in the heart and lung. Regulatory T cells (Tregs, CD4(+)CD25(+)FoxP3(+)) suppress inflammatory responses in...
7.
Jameel M, Xiong Q, Mansoor A, Bache R, Zhang J
J Mol Cell Cardiol
. 2016 Feb;
92:116-21.
PMID: 26854629
Congestive heart failure (CHF) is associated with intrinsic alterations of mitochondrial oxidative phosphorylation which lead to increased myocardial cytosolic free ADP. ATP sensitive K(+) channels (KATP) act as metabolic sensors...
8.
Kwon Y, Vant Hof J, Roy S, Bache R, Das G
J Card Fail
. 2015 Nov;
22(11):921-924.
PMID: 26571148
Background: We investigated whether a simple breath hold would yield dynamic oxygen (O) saturation change and whether the derived circulation time would be useful in assessing cardiac function. Methods And...
9.
Liu X, Kwak D, Lu Z, Xu X, Fassett J, Wang H, et al.
Hypertension
. 2014 Jun;
64(4):738-44.
PMID: 24958502
Studies have reported that development of congestive heart failure is associated with increased endoplasmic reticulum stress. Double stranded RNA-activated protein kinase R-like endoplasmic reticulum kinase (PERK) is a major transducer...
10.