Robert H Purcell
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Explore the profile of Robert H Purcell including associated specialties, affiliations and a list of published articles.
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122
Citations
6390
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Recent Articles
1.
Engle R, De Battista D, Danoff E, Nguyen H, Chen Z, Lusso P, et al.
mBio
. 2020 Nov;
11(6).
PMID: 33203756
Historical studies conducted in chimpanzees gave us the opportunity to investigate the basis for the different severities of liver damage and disease outcome associated with infection with wild-type hepatitis B...
2.
Chen Z, Engle R, Shen C, Zhao H, Schuck P, Danoff E, et al.
PLoS Pathog
. 2020 Sep;
16(8):e1008793.
PMID: 32866189
Transmission to chimpanzees of a precore hepatitis B virus (HBV) mutant implicated in acute liver failure (ALF) in humans did not cause ALF nor the classic form of acute hepatitis...
3.
Chen Z, Shen C, Engle R, Zamboni F, Kwong P, Purcell R, et al.
J Viral Hepat
. 2020 Mar;
27(8):847-851.
PMID: 32196859
Hepatitis B virus (HBV) is a major cause of acute liver failure (ALF) worldwide. While liver damage in classic acute hepatitis B is believed to be T-cell mediated, the pathogenesis...
4.
Alter H, Farci P, Bukh J, Purcell R
Clin Liver Dis (Hoboken)
. 2020 Mar;
15(Suppl 1):S64-S71.
PMID: 32140215
No abstract available.
5.
Chen Z, Diaz G, Pollicino T, Zhao H, Engle R, Schuck P, et al.
Proc Natl Acad Sci U S A
. 2018 Nov;
115(48):E11369-E11378.
PMID: 30420516
Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome leading to death or liver transplantation in 80% of cases. Due to the extremely rapid clinical course,...
6.
Boon D, Redd A, Laeyendecker O, Engle R, Nguyen H, Ocama P, et al.
J Infect Dis
. 2017 Nov;
217(5):785-789.
PMID: 29186448
A cross-sectional study was conducted of 500 human immunodeficiency virus (HIV)-infected adults frequency matched on age, sex, and community to 500 HIV-uninfected individuals in the Rakai District, Uganda to evaluate...
7.
Fontana R, Engle R, Purcell R, Lee W
Hepatology
. 2016 Sep;
65(1):389-390.
PMID: 27616011
No abstract available.
8.
Fontana R, Engle R, Scaglione S, Araya V, Shaikh O, Tillman H, et al.
Hepatology
. 2016 May;
64(6):1870-1880.
PMID: 27215797
Conclusion: Acute HEV infection is very rare in adult Americans with ALF (i.e., 0.4%) and could not be implicated in any indeterminate, autoimmune, or pregnancy-related ALF cases. Past exposure to...
9.
Kmush B, Labrique A, Li W, Klein S, Schulze K, Shaikh S, et al.
Am J Trop Med Hyg
. 2015 Dec;
94(1):203-11.
PMID: 26621563
Hepatitis E virus (HEV) infection is severe during pregnancy, with a pregnant case fatality rate around 30%. In Bangladesh, plasma samples from 1,100 women during the first trimester (TM) and...
10.
Sarkar S, Rivera E, Engle R, Nguyen H, Schechterly C, Alter H, et al.
J Clin Microbiol
. 2015 Sep;
53(11):3547-52.
PMID: 26338861
Hepatitis E virus (HEV) is considered a zoonotic infection in developed nations. A case of acute hepatitis E in a researcher following a scalpel injury while working on a pig...