Robert H Pullen 3rd
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Explore the profile of Robert H Pullen 3rd including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
29
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Recent Articles
1.
Pullen 3rd R, Sassano E, Agrawal P, Escobar J, Chehtane M, Schanen B, et al.
J Immunol
. 2024 Jan;
212(5):904-916.
PMID: 38276072
A primary concern in vaccine development is safety, particularly avoiding an excessive immune reaction in an otherwise healthy individual. An accurate prediction of vaccine reactogenicity using in vitro assays and...
2.
Pullen 3rd R, Abel S
Mol Biol Cell
. 2019 May;
30(16):2087-2095.
PMID: 31116687
T-cells use microvilli to search the surfaces of antigen-presenting cells for antigenic ligands. The active motion of scanning microvilli provides a force-generating mechanism that is intriguing in light of single-molecule...
3.
Pullen 3rd R, Abel S
Biophys J
. 2017 Jul;
113(1):120-131.
PMID: 28700910
Catch bonds are characterized by average lifetimes that initially increase with increasing tensile force. Recently, they have been implicated in T cell activation, where small numbers of antigenic receptor-ligand bonds...
4.
Mlynarczyk P, Pullen 3rd R, Abel S
J Chem Phys
. 2016 Jan;
144(1):015102.
PMID: 26747820
Positive feedback is a common feature in signal transduction networks and can lead to phenomena such as bistability and signal propagation by domain growth. Physical features of the cellular environment,...