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Robert H Lipsky

Explore the profile of Robert H Lipsky including associated specialties, affiliations and a list of published articles. Areas
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Articles 70
Citations 2269
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Recent Articles
1.
Lipsky R, Witkin J, Shafique H, Smith J, Cerne R, Marini A
Front Neurosci . 2024 Oct; 18:1446076. PMID: 39450122
Traumatic brain injury (TBI) has reached epidemic proportions worldwide. The consequences of TBI can be severe even with repetitive mild trauma. If death and coma are avoided, the consequences of...
2.
Witkin J, Shafique H, Cerne R, Smith J, Marini A, Lipsky R, et al.
Pharmacol Ther . 2024 Feb; 256:108609. PMID: 38369062
Traumatic brain injury (TBI) is a highly prevalent medical condition for which no medications specific for the prophylaxis or treatment of the condition as a whole exist. The spectrum of...
3.
Rosenthal E, Elm J, Ingles J, Rogers A, Terndrup T, Holsti M, et al.
Neurology . 2021 May; 96(19):e2372-e2386. PMID: 34032604
Objective: To quantify the association between early neurologic recovery, practice pattern variation, and endotracheal intubation during established status epilepticus, we performed a secondary analysis within the cohort of patients enrolled...
4.
Lin M, Huang W, Kabbani N, Theiss M, Hamilton J, Ecklund J, et al.
PLoS One . 2021 May; 16(5):e0251110. PMID: 33956875
The α7 neuronal nicotinic acetylcholine receptors (α7nAChRs) are essential for anti-inflammatory responses. The human-specific CHRFAM7A gene and its 2bp deletion polymorphism (Δ2bp variant) encodes a structurally-deficient α7nAChRs that may impact...
5.
Hendrix P, Foreman P, Senger S, Burkhardt B, Harrigan M, Fisher 3rd W, et al.
Neurosurg Rev . 2019 Jul; 43(4):1173-1178. PMID: 31332702
Loss of consciousness (LOC) at presentation with aneurysmal subarachnoid hemorrhage (aSAH) has been associated with early brain injury and poor functional outcome. The impact of LOC on the clinical course...
6.
Lin M, Griessenauer C, Starke R, Tubbs R, Shoja M, Foreman P, et al.
Mol Genet Genomic Med . 2019 Jul; 7(8):e737. PMID: 31268630
Background: Aneurysmal subarachnoid hemorrhage (aSAH) has high fatality and permanent disability rates due to the severe damage to brain cells and inflammation. The SERPINE1 gene that encodes PAI-1 for the...
7.
Huang W, Kabbani N, Brannan T, Lin M, Theiss M, Hamilton J, et al.
J Neurotrauma . 2019 Mar; 36(21):3026-3033. PMID: 30924722
The alpha 7 nicotinic acetylcholine receptor, α7 nAChR, plays a central role in regulating inflammatory responses. Previous studies showed that pharmacological inhibitors of α7nAChR have a pro-inflammatory effect, increasing the...
8.
Hamilton K, Wang Y, Raefsky S, Berkowitz S, Spangler R, Suire C, et al.
PLoS One . 2018 May; 13(5):e0196223. PMID: 29715265
Bhlhe40 is a transcription factor that is highly expressed in the hippocampus; however, its role in neuronal function is not well understood. Here, we used Bhlhe40 null mice on a...
9.
Foreman P, Hendrix P, Harrigan M, Fisher 3rd W, Vyas N, Lipsky R, et al.
J Clin Neurosci . 2018 Apr; 53:69-73. PMID: 29685416
The treatment of unruptured intracranial aneurysms remains controversial. The PHASES score was developed to predict the 5-year risk of aneurysm rupture. We have assigned PHASES scores to a cohort of...
10.
Hendrix P, Foreman P, Harrigan M, Fisher Rd W, Vyas N, Lipsky R, et al.
Nitric Oxide . 2017 Oct; 71:52-56. PMID: 29079038
Introduction: Cardiac abnormalities are observed frequently after aneurysmal subarachnoid hemorrhage (aSAH). A subset of aSAH patients develops neurogenic cardiomyopathy, likely induced by catecholamine excess. Genetic polymorphisms of the endothelial nitric...