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Robert H Cox

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Articles 16
Citations 214
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Recent Articles
1.
Sharma R, Al-Saleem F, Panzer J, Lee J, Puligedda R, Felicori L, et al.
Ann Clin Transl Neurol . 2018 Aug; 5(8):935-951. PMID: 30128318
Objective: Anti-NMDA receptor encephalitis (ANRE) is a potentially lethal encephalitis attributed to autoantibodies against the -methyl-D-aspartate receptor (NMDAR). We sought to clone and characterize monoclonal antibodies (mAbs) from an ANRE...
2.
Cox R, Fromme S
Cell Biochem Biophys . 2016 Sep; 74(4):499-511. PMID: 27638047
We have shown that three components contribute to functional voltage gated K (K ) currents in rat small mesenteric artery myocytes: (1) Kv1.2 plus Kv1.5 with Kvβ1.2 subunits, (2) Kv2.1...
3.
Cox R, Fromme S
Cell Biochem Biophys . 2016 Jun; 74(2):263-76. PMID: 27286858
Multiple K v channel complexes contribute to total K v current in numerous cell types and usually subserve different physiological functions. Identifying the complete compliment of functional K v channel...
4.
Cox R, Fromme S
Am J Hypertens . 2015 Mar; 28(10):1229-39. PMID: 25820242
Background: Enhanced function of dihydropyridine-sensitive Ca2+ channels (CaV) in hypertensive arterial myocytes (HAM) is well accepted. Increased protein expression of pore forming α1-subunits contributes to this effect, but cannot explain...
5.
Guo D, Yu M, Liu Q, Cox R, Liu T, Yan G
J Electrocardiol . 2014 May; 47(5):642-8. PMID: 24813353
Background: The late sodium current (INa-L) contributes importantly to rate-dependent change in action potential duration (APD) and transmural dispersion of repolarization (TDR). However, little is known about the mechanisms of...
6.
Cox R, Fromme S
Am J Physiol Cell Physiol . 2013 Aug; 305(8):C896-905. PMID: 23926129
Alternative splicing of the voltage-gated Ca(2+) (CaV) α1-subunit adds to the functional diversity of Ca(2+) channels. A variant with a 73-nt deletion in exon 15 of the Cav1.2 α1-subunit (Cav1.2Δ73)...
7.
Ren G, Jacob R, Kaulin Y, DiMuzio P, Xie Y, Mason R, et al.
Mol Genet Metab . 2011 Jul; 104(3):346-55. PMID: 21724437
The Smith-Lemli-Opitz syndrome (SLOS) is an inherited disorder of cholesterol synthesis caused by mutations in DHCR7 which encodes the final enzyme in the cholesterol synthesis pathway. The immediate precursor to...
8.
Sun Y, Quan X, Fromme S, Cox R, Zhang P, Zhang L, et al.
J Mol Cell Cardiol . 2010 Dec; 50(3):433-41. PMID: 21130771
A gain of function mutation N588K in the KCNH2 gene that encodes HERG channels has been shown to underlie the SQT1 form of short QT syndrome (SQTS). We describe a...
9.
Cox R, Lozinskaya I
Am J Hypertens . 2008 Feb; 21(4):406-12. PMID: 18246058
Background: This study was designed to test the hypothesis that differences exist in the inactivation properties of voltage-gated Ca(2+) channels (Ca(V)) in hypertensive arterial smooth muscle cells (ASMCs), and that...
10.
Cox R, Fromme S, Folander K, Swanson R
Am J Hypertens . 2008 Jan; 21(2):213-8. PMID: 18174882
Background: We have previously demonstrated differences in the gene expression of voltage-gated K v1.X channel alpha-subunits in arteries from Wistar-Kyoto rats (WKYs) and spontaneously hypertensive rats (SHRs). The purpose of...