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Robert E Miner 3rd

Explore the profile of Robert E Miner 3rd including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Smalley T, Nicolaci A, Tran K, Lokhandwala J, Obertopp N, Matlack J, et al.
bioRxiv . 2024 Oct; PMID: 39464070
Human Papilloma Virus (HPV)-related cancers are a global health burden, yet there are no targeted therapies available for chronically infected patients. The HPV protein E6 is essential for HPV-mediated tumorigenesis...
2.
Lokhandwala J, Matlack J, Smalley T, Miner 3rd R, Tran T, Binning J
Structure . 2024 Aug; 32(10):1711-1724.e5. PMID: 39173621
Protein glycation is a universal, non-enzymatic modification that occurs when a sugar covalently attaches to a primary amine. These spontaneous modifications may have deleterious or regulatory effects on protein function,...
3.
Maurin M, Ranjouri M, Megino-Luque C, Newberg J, Du D, Martin K, et al.
Nat Commun . 2023 Dec; 14(1):8444. PMID: 38114498
RNA splicing is an important biological process associated with cancer initiation and progression. However, the contribution of alternative splicing to pancreatic cancer (PDAC) development is not well understood. Here, we...
4.
Liu W, Miner 3rd R, Albaugh B, Ananiev G, Wildman S, Denu J
Biochemistry . 2022 Feb; 61(5):354-366. PMID: 35143176
Chromatin abnormalities are common hallmarks of cancer cells, which exhibit alterations in DNA methylation profiles that can silence tumor suppressor genes. These epigenetic patterns are partly established and maintained by...