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Robert Daber

Explore the profile of Robert Daber including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 487
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Recent Articles
11.
Raess P, Mintzer D, Husson M, Nakashima M, Morrissette J, Daber R, et al.
Blood . 2013 Oct; 122(17):3084-5. PMID: 24159168
No abstract available.
12.
Wertheim G, Daber R, Bagg A
J Mol Diagn . 2012 Nov; 15(1):27-30. PMID: 23159532
This commentary highlights the article by Spencer et al that outlines a novel next-generation sequencing-based method for the detection of FLT3 mutations.
13.
Izumi K, Mikesell H, Daber R, Chao G, Hutchinson A, Spinner N, et al.
Am J Med Genet A . 2011 Nov; 155A(12):3148-52. PMID: 22065607
No abstract available.
14.
Daber R, Chapman K, Ruchelli E, Kasperski S, Mulchandani S, Thiel B, et al.
Am J Med Genet A . 2011 Oct; 155A(10):2489-95. PMID: 21998853
Mosaic trisomy 17 is rare with only 28 cases reported and the clinical presentation is highly variable. The diagnosis is most commonly made by prenatal karyotype and in most cases...
15.
Daber R, Sochor M, Lewis M
J Mol Biol . 2011 Apr; 409(1):76-87. PMID: 21459098
The lactose (lac) repressor is an allosteric protein that can respond to environmental changes. Mutations introduced into the DNA binding domain and the effector binding pocket affect the repressor's ability...
16.
Milk L, Daber R, Lewis M
Protein Sci . 2010 Jun; 19(6):1162-72. PMID: 20512969
The Lac repressor has been used as a tool to understand protein-DNA recognition for many years. Recent experiments have demonstrated the ability of the Lac repressor to control gene expression...
17.
Daber R, Lewis M
Protein Eng Des Sel . 2009 Sep; 22(11):673-83. PMID: 19729374
Transcriptional regulation is an essential component of all metabolic pathways. At the most basic level, a protein binds to a particular DNA sequence (operator) on the genome and either positively...
18.
Daber R, Sharp K, Lewis M
J Mol Biol . 2009 Jul; 392(5):1133-44. PMID: 19631220
In both prokaryotic and eukaryotic organisms, repressors and activators are responsible for regulating gene expression. The lac operon is a paradigm for understanding how metabolites function as signaling molecules and...
19.
Daber R, Lewis M
J Mol Biol . 2009 Jun; 391(4):661-70. PMID: 19540845
Transcriptional regulation is a fundamental process for regulating the flux of all metabolic pathways. For the last several decades, the lac operon has served as a valuable model for studying...
20.
Daber R, Stayrook S, Rosenberg A, Lewis M
J Mol Biol . 2007 Jun; 370(4):609-19. PMID: 17543986
The lac operon is a model system for understanding how effector molecules regulate transcription and are necessary for allosteric transitions. The crystal structures of the lac repressor bound to inducer...